Seborrheic dermatitis free, 817 days and counting. See what I've been doing

The following is an email that was sent to me by one of the readers on this website. It outlines his journey and how he eventually stumbled upon a treatment that has been working for him. So here is Joakims – Nystatin Seborrheic Dermatitis Treatment:

I’ve struggled with SD for the last 5 years or so, and I had almost given up, but now I’ve found my solution. I realize people have SD to different degrees, so this might not be universal, but maybe you can help me reach the people at SkinDrone, and it might help some. Although, I think it will work for most people since it was so effective for me. I have no problems with SD any more. Not in my face, not in my scalp, not on my chest. All gone. I’ll begin with my story and then the solution (but to save you the suspense and disappointment if you already know about it and it didn’t work for you, it’s Nystatin).

Searching for a Treatment

I went to my doctor here in Denmark and he gave me Brentacort cream with hydrocortison (cortisol) and miconazol (some anti fungal). Now, I think we both agree that the steroid hormone cortisol cream is not the way to go. It makes the skin thinner and more sensitive in the long run. And I guess we are both in it for the long run, since there is apparently no permanent cure, only treatment and control. I also used nizoral shampoo and it made the scalp situation better, but again it didn’t really solve the problem. If I recall correctly, you had tried the same things with the same less-than-satisfying outcome. So, I just kind of came to terms with my condition since the visit to the doctors didn’t resolve the problem. I gave up on professional help.

Unexpected Remission

Last winter I went to the Philippines and the sun and salt-water made the seborrheic dermatitis go away – completely! I had no trouble at all even though both alcohol and poor sleep came along with me on that vacation. This gave me new hope, and I thought, there must be a way to get rid of it!

The Search Continues

So I started looking into the alternative treatments: I tried the salt-water treatment when I came back to Denmark, and I tried to sit in direct sunlight for at least 15 minutes a day – even during the cold and dark winter; I tried changing my diet – maybe it was the exotic food that had really cured me, while I was in the Philippines. I cut alcohol, coffee, milk (which actually did more than I care to admit), tried to eliminate bread and eggs and all sorts of stuff; I got fish-oil, extra vitamin-D and other dietary supplements; I went and bought a pure aloe vera extract and ordered Aveeno eczema moisturiser with colloidal oatmeal from Canada; I tried getting some time in the sauna regularly, since I had read somewhere that it might help; I tried to meditate; I tried drinking green tea every night and applying the teabag to my face. I literally tea-bagged myself to try to end this! I saw some progress, but compared to the amount of work involved and – which was far worse – the social stigma of not drinking neither coffee nor beer, it was just not worth it. Especially because I was not completely rid of the SD, it had only diminished. And I gave up on the alternative treatments.

My mother stayed hopeful and kept pushing me, so I went back to the doctor – desperate – and asked for something else. “I’ve tried everything, I don’t want cortisol, I’m open to alternative treatment, anything, what can you suggest?”. He said cortisol is the only way, but he was willing to send me to a dermatologist to finally determine if I really had SD or if it actually rosacea or something else.

The Last Appointment

So I pack my bag with all my alternative stuff that I want to present to the dermatologist. I prepare a speech to persuade him to consider alternative solutions. I’m so afraid that he will push the same damn cortisol cream on me, but I’m ready. I want to fight for another treatment. The dermatologist takes one look at me and says “oh, you’ve got SD, I’ve got just the thing for you”. I, half-joking/half-afraid, ask him if it’s a cortisol cream. “No no no, that’s the worst thing you can do. I’ve got something else for you, and I’m sure it will work wonders”. He gives me a prescription for another topical cream  and is ready to send me out the door. I’m so worked up at that point – my bag packed with pills and moisturisers that I’m ready to whip out and discuss, and my speech ready in the back of my mind. Because of all I’ve been through I find it hard to believe in this “miracle solution”. But he seems determined and tells me to come back if it doesn’t work. I haven’t talked to him since.

So what he prescribed to me is this Nystatin creme. It’s basically an anti-fungal without the steroid hormones. It’s a prescription drug in Denmark, but in Germany, he told me, it’s over-the-counter and you can use it almost as much as you want. But once every day should be enough. And it is. I was sceptical, but I gave it two weeks – still not drinking milk, and still watching out for beer and coffee – and it all went away. I never even applied it to my chest but the inflammation that I used to have there is completely gone. My scalp has also gotten better just from applying the cream to my face. I still use a shampoo with zinc pyrithione (like in Head&Shoulders, if I am not mistaken) and climbazole, but this is also over-the-counter and easy on the skin and hair.

How It Worked Out in The End

I can wear dark t-shirts again without getting dandruff all over them. I don’t have to worry about scratching my nose or running a hand through my hair. I don’t have to stay home in case I get a flare-up, because I don’t get those anymore. I tried to let go of the reins and have a beer or two, and maybe a cup of coffee, and still nothing. I don’t have to watch out anymore. Beer, coffee, exercise, and long, hot showers – and this is during winter with almost no sun. It’s just gone. For all I know I’m cured – you know, for good. I haven’t seen anything that resembles SD in 1½ months since I began the treatment – even though I’ve missed a few days here and there where I didn’t use the drug.

I think you can get Nystatin in the States as well: http://www.drugs.com/cdi/nystatin-cream.html but I’m not sure how the system works. Otherwise, have somebody send it from Germany where it’s just over-the-counter
If you are still struggling I hope this will help you. And I hope you haven’t heard of it before and just went “Oh, that. Yeah, that didn’t work for me”.

It truly changed my life and I hope it can do the same for you and all the readers of SkinDrone.

Thank You

Thank you Joakim for taking the time to write about your experience. It is detailed information like this that can help others who are likely taking the same path as you. When reading the email myself there were many parts that closely related to my own experience. Glad to hear that you have found a seborrheic dermatitis treatment that works for you. Once again, thank you for taking the time to write this and I hope it is useful for others.

Seborrheic dermatitis free, 817 days and counting. See what I've been doing

About Michael A.

After being affected by seborrheic dermatitis, I have made it my goal to gather and organize all the information that has helped me in my journey.

Your Guide to Seborrheic Dermatitis

Your complete resource to everything I've learned about seborrheic dermatitis:

What causes seborrheic dermatitis

How to best treat seborrheic dermatitis

Are antifungal treatments the best approach

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231 Responses to “Nystatin A Potential Seborrheic Dermatitis Treatment”

  1. Matthew Profile Photo
    Matthew

    received my nystatin cream yesterday and tried it for the first time and the cream is yellow and very thick? It is a brand called nystaderm, was just wondering if all nystatin creams are this colour and consistency or have i bought the wrong type.

    Reply
    • Joakim Profile Photo
      Joakim

      Mine has a yellow/grey hue, but it is not straight up yellow 🙂 if you got the cream, then I think you’re good to go. The paste might work as well. I wouldn’t use the gel. That seems like it for oral use.

      I hope you’ll see some good results!

      Reply
    • Matthew Profile Photo
      Matthew

      Just wanted to pop a quick message on here to say thanks to Joakim for this information, Nystatin has greatly improved my seb derm, its still not gone completely and been using 3 weeks now but it is so much better and i am hoping it will continue to improve. I had used steroids for quite some time so i think that is the reason it is not a quick fix. I also found that Nystatin Acis worked alot better than the Nystaderm, as Nystaderm seemed to cause alot of pimples but Acis does not. Thanks once again for this article as it has brought me alot of relief 🙂

      Reply
  2. Matthew Bennett Profile Photo
    Matthew Bennett

    Hey Joakim,

    I was just wondering did you end up trying out Brentan and did it work for you? I’m currently trying out a miconazole cream and have a tube of nystatin on its way to me. Hoping it will work for me as I have tried everything. The miconazole cream so far has reduced itching and redness on my nose but not fully healed yet but it’s early days and seems to be quite promising. If anyone is based in U.K I am using Dakarin (athletes foot cream) and ordered the Nystatin from pharmasana.co.uk

    Reply
    • Shane Profile Photo
      Shane

      The Nystain cream really worked for me. I’m still using it a year and a half later. Once or twice a week and it basically keep it’s at bay. Handy that you found some where in the UK that stocks it! The nearest outlet I found was Germany. I might try that place in the UK it’ll be quicker as I’m in Dublin. Shane.

      Reply
      • Matthew Profile Photo
        Matthew

        Hey Shane,

        It is a German site but it ships to the UK so it still will have to deliver from Germany unfortunately, I just couldnt find any other sites that allowed shipment to the UK.

        The miconazole cream dried my skin out ridiculous amounts and ended up making the situation worse so I’m looking forward to receiving the Nystatin and see if it works.

        Reply
      • Sahila Profile Photo
        Sahila

        Hi shane
        Could you please give me the full name of the nystatin cream. I live close to germany and want to get a tube but saw online there are several kinds of nystatin cream. I hope you can reply. Thanx in advance. Sahila

        Reply
    • Joakim Profile Photo
      Joakim

      Hey Matthew,

      I did try Brentan, but it didn’t work as well as I had hoped. If I recall correctly my doctor recommended it as an alternative to nystatin, since he couldn’t prescribe nystatin to me and I would have to go see a dermatologist every time. But now he has received the certification, or whatever, that he needs in order to prescribe nystatin, so I started using that again. For me that seems to be the best option 🙂

      Reply
  3. Lasse Profile Photo
    Lasse

    Jeg glæder mig til at skrive min læge en forespørgsel på nystatin creme i dag. Jeg holder dig underrettet 🙂 Fedt at det virker for dig! Det er da verdens tarveligste sygdom.

    Google Translate:
    I am looking to write my doctor a query on Nystatin cream today. I will keep you informed ? fat that it works for you! It’s the world’s meanest disease.

    Reply
    • Joakim Profile Photo
      Joakim

      Dermatologen jeg snakkede med sørger vist for at få cremen specialimporteret til apoteket ved Rundetårn i København. Jeg ved ikke, hvordan man skal bære sig ad, hvis du er et andet sted i landet, men det kan være din læge har en ide 🙂 det bliver spændende at høre resultatet, Lasse! Held og lykke.

      Reply
  4. Arturo Profile Photo
    Arturo

    Hey man i had went to my doctor about 3 and half years ago for an itch and white spot on my scalp that wouldnt go away right away he prescribes me this nystatin cream USP 100,000 nystatin units by perrigo apperently its mainly used for like vaginal infection and baby rashes and fungus cause he said i had a fungus infection . So i apply a small amount everyday and the first week the itching stops and i didnt even have to use it a full month cause i got lazy and it had all went away . 3 years later pass and it came back hard ! I think it was because i started to use a dandruff shampoo everyday thaat i didnt really need . And it was so itchy so i went to a different doctor because mines had moved , this one tells me i have seborrheic dermatitis and that it was chronic and prescribed me some shampoo that was 25 bucks ! Didnt work in fact i have been using fresh aloe vera leaf cutting them and applying the gel directky to the scalp once or twice a week every other week of the month and it works for the itch ,hair growth and with dandruff .BUT sd is still there and i finally found my tube of nystatin that worked for me years ago behind my bathroom sink ! Im excited to try and see if it will renew my sd free scalp for some more years will keep yall updated wish me luck i have been looking for this tube since sd came back !btw its easy for me to apply because i cut my hair machine bald as i notice long hair makes your hair snow lol and itchy af.

    Reply
  5. Håkan Profile Photo
    Håkan

    Hi

    After over 10 years of facial SD I found a water based spray with glycerol and formic acid, that clears my skin. Just three ingredients.

    Formic acid is the natural acid that ants spray when they get attacked.

    The spray doesn’t dry the skin and the smell goes away after a few seconds. Don’t use it in mouth or eyes.

    I by it at myracid.com.

    Håkan
    Sweden

    Reply
  6. happygal Profile Photo
    happygal

    I would like to see a shampoo made with Nystatin. It works well for me too and I’d use it on my scalp if my hair didn’t get in the way.

    Anyone up for making a shampoo with it?

    Reply
  7. Jack Leaoff Profile Photo
    Jack Leaoff

    Guys please somebody tell the result of nystatin being applied to scalp.I have only SD in my scalp.In previous posts it is said that when we applied our face chest and scalp SD gone too.Sİnce I have no SD in my face I don’t want to apply to face.What is the new opinions about applying to Nystatin to scalp?

    Reply
    • Joakim Profile Photo
      Joakim

      Hi Jack,
      I am pretty sure you can use it, but it’s just difficult to apply for me. I have fairly long hair, which makes it difficult to apply nystatin to my scalp in a controlled fashion. So I prefer the zinc pyrithione and climbazole shampoo.
      But if are able to apply small amounts to the areas where you have symptoms, I think you should be fine. Ask your doctor or at the pharmacy for professional advice. It might induce hairloss or something I am not aware about.
      Best, Joakim

      Reply
  8. JM Profile Photo
    JM

    Well, it’s a few months since my initial post, and I’m still SD free!
    Last week, I had 2 little red patches on my chest, but an application of the Panderm cream made this go away overnight.
    I thought I’d share a few other things I’ve changed in my lifestyle, which might help others still looking for that elusive “cure”.

    After a discussion with a Bioderma specialist in a Boots Pharmacy, I was recommended to use their Sensibio DS+ Gel to wash my face. You can use it all over your body too. Prior to that, I was using some Neutrogena Pink Grapefruit Acne wash, but I think this was too drying.

    I still use Head & Shoulders to wash my hair.

    I never put my head/face under a hot shower. I tend to shower in lukewarm water because it’s so hot over here.

    I use a Bioderma moisturiser twice daily.

    About 7 weeks ago I started following aspects of the Paleo lifestyle in my diet. I cook all food from scratch, and now use Coconut Oil for all cooking. Don’t be put off if you don’t like the taste of coconuts, as the brand I use doesn’t taste of coconut at all, so just find a brand you are happy with. Another bonus of this lifestyle change is that I have lost almost 7 kilos (just over a stone).

    I take a probiotic and digestive enzyme supplement daily. The first brand I tried, you had to take one capsule before every big meal, which was sometimes inconvenient.
    I now use a brand called Maxxiprob, which you only take once daily. Each capsule contains 4 billion cultures. I’ve suffered from heart burn/reflux all my life, especially after I’ve been drinking alcohol or eating unhealthily for a day or two. I was taking a 150mg Zantac pretty much every other day because of this, but since taking the Maxxiprob I don’t get heartburn, and I also don’t get the stomach cramps I used to get a few hours after eating spicy food.
    I used to get flare-ups after drinking red wine, but that doesn’t seem to happen anymore either.

    Incidentally, the Panderm cream seems to be made here in the UAE. I don’t know if there are similar alternatives where you live, but here are the ingredients in Panderm (cream, don’t use the ointment):

    Nystatin: 100,000 units
    Neomycin Sulphate equivalent to 2.5mg
    Neomycin base
    Gramicidin 0.25mg
    Triamcinolone acetonide 1mg

    I hope the above is useful to anyone still looking to conquer this terrible condition.

    Reply
  9. Nye Profile Photo
    Nye

    Hello,

    I just want to chime in and say that Nystatin has been working quite nicely for me the past 4-5 days. It all started when I moved to the states from tropical country (Thailand) when my SD flared up. Back at home, I didn’t have to use any thing to control the SD and I would be fine. I noticed a bit of scaly buildup on my T-zone but it was invisible for the most part. I had been on steroid before and I am on 12 months withdrawal period at the moment. My routine back then was to not stressed and eat healthily, take supplements, all that good stuff. I only use cleanser by the way.

    It was dandy until I had to take flight for 14 hours to US that my SD became uncontrollable. And for few days after, there it was, the biggest flare-up of my existence. It’s like SD lied dormant just to sprang out to mess with you personally. I believed it was the weather (LA may seems like a warm place for you people, but for SEA people, it is very chilling) that aggravate my skin, not to mention the stress that came with it. My face was, excuse my language, SO FUCKING RED. I thought it emited red light on its own, to be honest. The scale was so rough and the itch unbearable.

    I have been reading this site for sometimes before so I knew of Nystatin, but wouldn’t use it for the sake of resting my skin from steroid. Besides there wasn’t any bad flare back in Thailand. I was not familiared with how pharmacy works in US, but I had to get something to alleviate my burning SD. So after meeting with a doctor (Surprise, surprise he asked whether I want him to precribe steroid cream instead. Dammit modern medicine! This is exactly why people resent you and become anti vaxxer and whatnot.) I told him to precribe Nystatin cream. And there I got it, the Nystatin ointment.

    I didn’t know prior to that moment that ointment and cream are not the same. Ointment is oily and cream is less oil, more water hence creamy. When the pharmarcy gave me ointment I didn’t know better. It was Nystatin ointment 100 000 USP called actavis or whatever (I want to convince you that this is not an ad, any nystatin brand is okay in my book). Anyway, i used it regardless. It took three days, but my SD eventually subsided. Hooray! It is not yet gone mind you, but the redness is reduced to faint pinkish hue. And it is not itching or scaly anymore, albeit a bit flakey on eyebrows. Keep in mind this is 3 days result from the worst flare up of my life. The best thing is, I don’t feel my skin thinning, burn, or behave erratically aside from SD so that’s also a win.

    The thing is, Nystatin ointment, while great, is hard to wash off since it is petroleum based. So I will be calling the pharmacy to change it to cream. I believe that when it is in cream, it will heal even faster, no? I don’t know whether this site admin is still active but I just want to share my result.

    Oh and by the way, ointment is pure nystatin while cream has other ingredients like glycerin and water. Both have same USP of 100 000.

    tl;dr I calmed the worst flare up of my life using Nystatin oinment. But I rather get the cream one. I hope it will work for me as well as it is for Joakim.

    Reply
    • Joakim Profile Photo
      Joakim

      Hi Nye,

      in my experience it took more than 4-5 days for the symptoms to completely disappear. I think that took something like 1-2 weeks in my case. But it sounds like you are at least back to a bearable level. Hopefully, your progress has continued the last few days.

      There should be no problem for you using the nystatin ointment in relation to your steroid resting period. At least the one I got has no steroids whatsoever, so if that is not the case for you, maybe try a different brand. Maybe I just misunderstood your concern 🙂

      I haven’t tried the ointment, but intuitively I think I also prefer the cream. I have bad experience with thick ointments and petroleum-based products, but maybe it doesn’t matter if it contains and active ingredient that kills the yeast. I think you should be fine, but yeah, maybe change it up in the future.

      I have my fingers crossed for your continue progress and SD-free face!
      Best regards,
      Joakim

      Reply
      • Nye Profile Photo
        Nye

        This is a report on my symptom after week 2 of using nystatin ointment.

        So the first 9 days were great! My skin was back to normal and I didn’t have to carefully monitor what I eat, just not binge on junk foods and I would be fine. However, after day 10 til now, I have found that SD is creeping up back on my face, albeit way less severe than before. It is still at an acceptable level and I can still socialize with people, but it is just plain annoying to see inflamed nose creases all the time. Luckily still yet any bad breakout. I suppose it’s the petroleum based gel nature of it (since I use ointment instead of cream) that aggravate the symptom and feed the fungi. And because I panicked for a bit, I lathered layers of the ointment several times in the last few days which may further attributed to the symptom.

        So, I’m going to get the cream one instead after I finish typing this comment, wish me luck!

        Anyway, Joakim, is nystatin still working for you? And how’s the effectiveness of it overtime? From a nystatin ointment user perspective I feel like it may be just another ketoconazole that the fungi will eventually adapt (Please god no) and lose it effectiveness. But I willing to bet nystatin cream, with its water based texture would be better. Oh and please tell me how you are using it in details, like do you apply it immediately after shower or do you wait for fifteen minutes, something like that.

        Personally, I use it after shower, in the morning and before bed. If I feel itchy on certain places I will apply it regardless. I think the excessive applications made my SD came back so I gonna try applying a thin layer of it after shower in the morning after my face has dried off instead.

        PS. mine has no steroid ingredient although this same brand (actavis) also have nystatin with steroid one, so I’m going to be very precise when I order another tube.

        Wishing you people who are suffering with SD all the best,
        Nye

        Reply
        • Joakim Profile Photo
          Joakim

          I’m sorry to hear about the upset. My only consolation is that nystatin continues to work for me.

          I think initially, I would apply the cream after showering in the morning, probably only once everyday, but my dermatologist told me that two times were fine as well. However, if you feel like you are clogging up the skin, then I’d suggest dialing it down to just once a day. Then just be patient with the results. It took something like two weeks for my symptoms to disappear completely, but I say improvements after just one week.

          As for the effectiveness, I am still using it now more than 1½ years after trying it for the first time, so I’m surprised that you see a recurrence after just 9 days. Maybe it’s the ointment, I wish you the best.

          And the details: I tried to be patient in the beginning and not lather my face with the creme, so that my skin could still breathe. I applied it once every day after showering, carefully padding my face with a towel, so as to not disrupt my skin – which was still very sensitive back then – and then applying a small amount, but enough to cover everything: Nose, forehead, eyebrows, and patches on my cheeks and chin. I didn’t wait a certain amount of time – I just tried to keep my showers as short and cool as possible. Hot water would always make my nose peel like crazy.

          These days I am more care-free. I try to remember to apply it daily, but if I miss a few, then there’s no upset at all. And I don’t watch my diet or coffee or alcohol or anything. At the moment I have a small amount of redness around my nose, but I think I have forgotten to use nystatin for a week and I have been stressed out, not sleeping enough, and winter is coming. But I am certain that I will have it under control in a few days of more careful attention. I hope it will be the same for you after you get the creme 🙂

          Reply
          • Nye Profile Photo
            Nye

            Hi Joakim. Reporting back,

            I got my nystatin cream from the pharmarcy this afternoon. This time the brand name is Qualitest (last time it’s Actavis). I applied it sparsely on inflamed areas in the afternoon and later after evening shower.

            It’s currently 11pm and my face is now back to normal! Within one day!

            Redness around nose creases reduced significantly and on other parts it’s practically invisible. I hardly could believe it since I just had a pizza and 5-6 pieces of chocolate chip cookie for dinner, with chinese foods for breakfast and lunch. Normally redness would reduce after I take a nap or sleep, but this time it is just slowly fading on it’s own as the day progress.

            This simply strengthens the hypothesis; nystatin ointment is not a good alternative to nystatin cream. I will try it for another week or two to see how effective it will be in the long run but for now I’m pretty confident in it. So for any SD sufferers reading this wanting to try nystatin, tell your doctor to prescribe nystatin CREAM not OINTMENT and definitely one without steroid ingredient.

            Thanks for all the information Joakim. One question though, are you taking holistic approach like Michael as well? I personally don’t believe that SD is “uncurable”. But will take a lot of effort to change your health and gene expressions (as in epigenetics) to the point that it eliminate your SD altogether which may require radical change of your life. Since the truth of SD being uncurable came from the same people that would eagerly prescribe you hydrocortisone, I’m willing to hold onto my belief that it could be cured.

            Have a good one and thanks again,
            Nye

          • Joakim Profile Photo
            Joakim

            Great news! I hope it’s not just a fluke.

            No, Michael and I have different approaches at the moment. But I did learn a lot of good stuff from his site before I found nystatin. I just never got my SD to a controllable level without nystatin on a reliable basis. I mean, sometimes it would be fine, but I would always worry about what my face would look like in the morning. I think Michael has developed his regimen in the meantime, so that might have changed, but for me it is just such a relief that I don’t have to worry about tomorrow – and I don’t have to worry about today either: you know, if I have pizza and a coffee today, will my face blow up tomorrow.

            So Michaels solution works out for him – and probably a lot of other people as well, but I wouldn’t know, since I just monitor this page – and mine works for me. I don’t think that any of us claim that our solutions will work for everybody, but we both offer alternatives that we hope will work for some. It amazes me how many people seem to have found a way to manage their SD through my post on Michaels site.

            But I like to think that SD is curable. And if you want to go down that road and find a balance without the medicine, then best of luck! Either way, I think that nystatin will help you get back on track. Knock the symptoms down for 2 weeks or a month or so and allow the skin to regenerate a little. I think it will be easier to keep the SD down with proper food/exercise/cleanses then.

  10. JM Profile Photo
    JM

    I’d just like to say that this website and especially the information on Nystatin has basically changed my life. I’ve suffered from Seb Derm for over 25 years, and have spent thousands on pretty much every “cure” you’ve mentioned on your site, along with some others I’d found elsewhere on the web.
    I’d basically gotten to the point where I was using a strong (1%) steroid cream and Nizoral cream on my face twice daily, which I had done for around 5 years.

    I live in Dubai, and have had trouble finding a Nystatin cream, but a Chemist recommended “Panderm” to me. It contains Nystatin, as well as a few other anti-fungal and anti-biotic ingredients. I was having a really bad flare up, but after 1 week of applying twice daily to my face, all my symptoms were gone! Even the constant “itchy” feeling on my face has disappeared. It’s now been a month, and I’m still using the cream daily as I’m a bit afraid to stop, but I will gradually try using it once every two days, then reduce further.

    I wouldn’t have found this “cure” without the information on your site, and I hope my experience can help others who suffer from this horrible and (at times) embarrassing condition. It appears there’s also a “Panderm Plus”, but I just use the normal “Panderm” (cream, not the ointment). It’s in a white and yellow tube. It’s also very cheap, at AED 11 for a tube, so about £2 or $2.50.

    Thanks again for your site. It’s a great source of information.

    Reply
    • Joakim Profile Photo
      Joakim

      Hi JM,

      great to hear that you recovered after such a long time with SD! I’m very happy for you, and that this post, made more than 1½ years ago, continue to help people.

      In my experience, once I became symptom-free for a while, it took the SD longer to come back. I think that by allowing your skin to get back into a normal state by using the cream, it gets more difficult for the yeast to disrupt it again.
      So hopefully you will be able to dial down on the administration of drugs.

      All the best to you in the future!
      Joakim

      Reply
  11. Marc Profile Photo
    Marc

    Hello,

    Need some serious help in regards to nystatin. To those that had success using Nystatin, is their a difference between the cream and paste form. The 50g tube that I purchased is in paste form. Would it still be ok to use?

    Reply
  12. Marc Profile Photo
    Marc

    Hello,

    Today I received my Nystatin 50g tube from Amazon German website. However I’m a little worried to try it out. Can anyone please share their experience using Nystatin bought from the Amazon German website. How is it being applied and when should I apply it? Is it safe?

    Thank You

    Reply
    • Joakim Profile Photo
      Joakim

      Hi Marc,

      there are a lot of comments in this thread by now, and not all of them apply to your questions, but some of them do. People have been asking questions and posting their experiences for a little more than year and a half now. If you want to, you can scroll through and get a glimpse of what people have been saying. Also, isn’t there a piece of paper in the container that describes possible side-effects and how to apply it and such?

      I think I can honestly say that I have read every comment posted here. The large majority of people see either an improvement of their SD or no effect at all. A few people reported that they reacted to some of the stabilizing ingredients in the creme with acne as a result. If you want to read into this do a ctrl+f for the guy called Ian, who wrote about this in detail.
      But I would expect that you either get rid of your SD, or reduce it by like 95%, or nothing much happens at all.
      You can also read about it online to get a better idea, or ask your doctor if you are still unsure about it.

      Apply a small about to the inflamed areas once every day. Just enough that it absorbs into the skin – don’t lather it on to leave a layer behind. Do it in the morning or evening or whatever fits into your schedule. I usually do it after I shower.

      I think it’s good that you don’t take our advice for granted. We are, after all, just strangers on the internet. Probably not even a doctor among us! 🙂 So if you have concerns, maybe consult a professional.

      I wish you the best of luck!
      Joakim

      Reply
  13. Andrew Rocha Profile Photo
    Andrew Rocha

    Hello my name is Andrew I live in Houston, Tx I have had SD for 9 yrs on my forehead, ears, sides of my nose and I have had small patches of hair that will not fully grow back. Anyway I was skimming the Internet looking for answers and found skin drone and reading the group comments nystatin. I was very excited and began looking at the posts with links to Amazon in Germany and looking to purchase. On that day I was in my wife’s side of the bathroom and there was a brand new box of Nystatin, I was floored that this product was in my house. I asked my wife recently why she had it and she said when my baby son was breast feeding she got a red rash on her nipple and she put ointment on it and it wouldn’t go away. She told my son’s predatrician what was going on with her and she prescribed nystatin said my son my have thrush and when he breast feeds he keeps reinfecting the wound. My wife applied at night the next day it was gone and never had to use it again. So here I am with a new tube but unfortunately for me it was not an instant cure but I do see an improvement just very slowly. I was curious to know if anyone has had patches of hair loss due to SD and if so what do they recommend?

    Reply
    • Marc Profile Photo
      Marc

      Hello Andrew, I’ve been suffering from SD for 5 years now. my affected area is my eyebrows mostly on my right, and I do have patches of hair missing on my eyebrows. I want to confirm that you purchase your Nystatin from a German Amazon website and received it here in the US. Would you have happen to recall how long it took for you to receive it after purchased?

      Reply
      • Andrew Profile Photo
        Andrew

        Hey Marc, my wife was original prescribed here in Houston, TX and it seemed like it was not working. I recently bought it from Amazon/Germany and it took about two weeks and I have not tried it yet. I kinda was giving up because I didn’t see results in 30 days so I completely stop the weird thing is lately I have seen the redness reduce a whole more then I have ever have. So I’m gonna get back on it to see if it keeps clearing up. Good luck to you!

        Reply
        • Marc Profile Photo
          Marc

          Andrew, so you haven’t tried the you purchase from the German site? Are you continuing to use the one your wife was prescribed with? Would you be able to compare the one you received from Amazon to the one your wife was prescribed with? I wanted to see if their is any difference between the two.

          Thank You in advance.

          Marc

          Reply
  14. Joakim Profile Photo
    Joakim

    So, nystatin lederle creme – the one I used to use – seems to have been pulled from the market for whatever reason. It’s apparently not just the german amazon. I went to my pharmacy in Denmark recently to pick up a new tube (#3 since starting 1½ years ago) and couldn’t get a hold of my regular stuff either. Instead they gave me Candio Hermal Creme from Almirall. It is also available at the german amazon: http://tinyurl.com/jhywgyd.

    I haven’t tried it yet, but I’ll let you know if it works.
    Also, Mark and Shane, can you please give us an update on the nystatin acis creme, which also seems to be an alternative?
    They both have the same amount of nystatin per gram, so I guess they should work equally well. It’s the same amount as the old brand as well, so everything should be fine, but maybe – just maybe – the remaining ingredients play a role.

    I think the german amazon also ships to the US. I read a request not that long ago. You can change the language to english on the site, so it shouldn’t be too difficult to place the order.

    Hope you’re all doing well!
    Best regards, Joakim

    Reply
    • Joakim Profile Photo
      Joakim

      Update:
      The new creme that I got works equally well. My SD is still under control 🙂

      Reply
  15. Marc Profile Photo
    Marc

    How are you guys paying for this nystatin? and how long does it take to get shipped to US. I really need this. Can I get else where.?

    Reply
  16. Andrew Profile Photo
    Andrew

    Can you elaborate on the potency of the cream from Germany? Here in the states its watered down version in other words less poetency!

    Reply
    • Joakim Profile Photo
      Joakim

      It says 100.000 I.E. on the packaging of the 25 g tubes. I think it translates into about 20-25 mg per tube, but I’m not sure.

      Reply
      • Joakim Profile Photo
        Joakim

        Hold up, I got it mixed up. It’s 100000 i.e. or 22.72 mg Nystatin per 1 g of creme – not the whole tube, as I said before.

        Reply
        • Andrew Rocha Profile Photo
          Andrew Rocha

          Hello all, I have been suffering from SD for more than 9 years and it has been so frustrating for me as I am sure many of you know what I am talking about. I found this site searching for a cure and was excited to see some good responses and began looking on line to purchase nystatin. Low and behold one day my son that is 2 yrs old got a rash on his bottom that looked severe and we took him to the Dr.’s because the normal diaper rash cream was not working. The Dr. prescribed him a cream and we barely put it on the rash and later that day it was gone and never had to use the cream again then it was shelved. I never realized what I had in my possession the whole time it was Nystatin. I was so happy because I know no one in Germany and it was given to us in Houston, TX. I put it on and there has been no good responses for me unfortunately, It has USP, 100,000 units per gram, 30 gram Mfd by Taro Pharmaceuticals Inc. Bramptom, Ontario Canada. Dist by: Taro Pharmaceuticals U.S.A Inc. Hawthorne, NY
          is this the same as the German version that has worked for many of you? Or is the German version a much stronger dosage?

          Reply
          • Joakim Profile Photo
            Joakim

            Hi Andrew. Sorry to hear that the cream didn’t work for you. Did you try to use it for 2 weeks, or did you simply put it on once?

            It’s the same dosage as the german one that I have been using. Maybe it doesn’t work for you for whatever reason, as many others have reported. Sometimes it appears to be a swing and a miss.

            You mentioned hair-loss in another comment, right? Are you sure that your skin disorder is SD, and not something that looks similar?

            All the best,
            Joakim

          • Andrew Rocha Profile Photo
            Andrew Rocha

            Hello Joakim, I have been to several derms in the Houston area and 3 of derms told me it was Seb derm and 1 said it looked to be a mixture of rosacia, Seb derm, and psoriasis. I have tried all types topical creams like a lot of you have and nothing seems to work including nystatin. I am still using nystatin twice a day in the morning and at night hoping for a different result. I have ordered the German version hoping that it may be different then the version I have. If anyone can recommend a Seb derm dr. In the US I would appreciate it . Thanks

  17. Mark Profile Photo
    Mark

    Hi all, it says that Nystatin Lederle Cream is unavailable on Amazon, has anyone sourced it anywhere else ? Thanks

    Reply
    • Joakim Profile Photo
      Joakim

      Hey Mark,

      I think the reason why Nystatin is being discontinued on amazon – and why I had to get it from Germany — is that it’s sort of an old school medical remedy. My dermatologist who recommended it in the first place was sort of old, so I wouldn’t be surprised if he practiced old school medicine.

      I went to my regular doctor’s the other day, and he told me that he didn’t really believe in nystatin despite my success, and he defended the standard treatment using the mixed formula of hydrocortisone and antifungal ingredients and an antifungal shampoo. I expressed my concern about the hydrocortisone because it makes the skin thinner and more sensitive in the long run. And then we sort of came to a middle ground.

      The hydrocortisone is not really essential to the treatment of SD, since we just want to go after the fungus. Yet, it is the hydrocortisone component – not the antifungal – that limits the use of the formulation and restricts us to only something like one or two weeks of continued use. My experience with a remedy like these, e.g. Brentacort which I was prescribed, is that it works wonders as long as you use it, but within weeks you’re in remission with SD all over your face again.

      My doctor is not very fond of nystatin, though, for some reason that I didn’t really understand, but hey, I don’t have a medical degree (keep that in mind ;)). So he basically suggested another antifungal, I guess a newer, modern formulation, that doesn’t contain the hydrocortisone and that you can apply for extended periods of time. He suggested Brentan, which is over the counter here in Denmark and contains miconazole, a type of antifungal in the same “familiy” as the one in my shampoo (climbazole). I haven’t had any experience with this or other pure antifungals, but I like the idea. Nystatin is probably not a miracle drug, but the miracle effect is that you can use it for a long time and really get rid of the SD and allow your skin enough time to heal and regain a strong barrier and balance. Maybe you can get this effect from other antifungals just as long as they don’t also contain hydrocortisone so that you’re limited to 1-2 weeks.

      Of course, don’t take my advice for medical facts, but as inspiration. Talk to your doctor about hydrocortisone-free alternatives. Get his opinion on nystatin, or perhaps another antifungal. Maybe Brentan?

      Nystatin worked for me and I’m very happy that I did, so if you cant get it where you are, try other antifungals and if they don’t work, then you can go through the hassle of acquiring nystatin, but for all I know it’s not necessarily the only option. I just finished my last tube of nystatin, but next winter I’m thinking of trying Brentan instead, if I get into trouble. It would be interesting to see if there’s a difference 🙂

      As always, best of luck!

      Reply
      • Mark Profile Photo
        Mark

        Thanks, it was the German Amazon I was trying to get it from, the same cream as you got, it says not available. I got another version, Nystatin Acis creme, so hopefully that will be fine. I did read on another site, a guy who was recommended to take a small bit of Nystatin powder to heal his gut from the inside and his SD cleared up really quickly. Cheers

        Reply
        • Shane Profile Photo
          Shane

          Mark keep us informed on how the ACIS version of Nystatin worked out for you! Shane.

          Reply
          • Shane Profile Photo
            Shane

            I can’t seem to source it any where online. I have a friend who lives in Germany and I asked him could be try a few pharmacies there and post it over to Ireland. He found it and sent it on, but when it arrived it was Nystatin Acis. Which I believe is already available. So far the Acis seems to be working so maybe this version is as effective as the one we can no longer get.

  18. Joseph Byrd Profile Photo
    Joseph Byrd

    I have suffered for 3 years with constant itching, stinging, flaking, redness around my nose and under my eyes. It then spread to my hairline and increased in intensity. My flares were so bad, and noticeable, that I was embarrassed to show my face in public. I was diagnosed last fall with sd. I have tried every natural remedy known for treatment of this. Nothing worked. My doctor told me to wash with selsun selenium sulfide shampoo, and that definitely calmed it down, but my face was still red, and I had flares a couple times a month. I took the advice of this email, and started using nystatin cream last week. I apply it two or three times a day, and my sd is all but GONE! I am completely amazed at how quickly this worked, when nothing else I used ever did. I still use the selsun in conjunction with it, and will continue to do so, but man oh man, I am ecstatic with the results of the nystatin! I honestly believe that sd is a yeast infection related skin disorder, and that this treatment will work for most people.thank you so much for this very informative article. God speed 🙂

    Reply
    • Joakim Profile Photo
      Joakim

      Great news! I’m very happy to hear that, Joseph 🙂
      I think it’s a good idea to stay on top of the dandruff as well with the shampoo, while keeping the inflammation in the face in check with the nystatin. Even though my dandruff improved when I started using the nystatin in my face, it has not completely disappeared and during winter it can still reach levels where I’m very aware of it and avoid black shirts and such. This winter I didn’t use my usual dandruff shampoo, though, so that might be the cause. Anyway, the shampoo is probable a good idea to keep around! I am happy to hear that you can go back to a life without SD ruining your public appearance and self-esteem 😉 Stay healthy.

      Reply
  19. Vero Profile Photo
    Vero

    Hi – this is in response to Marc – below a link from an Amazon.de pharmacy that delivers to the UK and probably also to other countries? Hope this helps.
    I am still very grateful to Joakim for pointing out this cream and for Michael for the blog and research which is so interesting and makes so much sense. My use is less frequent now but the effect of the Nystatin is always almost immediate after a flare-up and after about 12 months of on and off usage. Great stuff, thanks again for the tip and this great forum.
    http://www.amazon.de/NYSTATIN-LEDERLE-Creme-25-g/dp/B00DIWOVCK/ref=pd_sim_sbs_121_2?ie=UTF8&dpID=41E%2B-UgqFML&dpSrc=sims&preST=_AC_UL160_SR160%2C160_&refRID=0M4H63JBWCBE4J0JVBD2

    Reply
    • Joakim Profile Photo
      Joakim

      It really makes me happy to know that I have helped someone else deal with their SD 🙂
      So thank you for that, Vero, it’s great to hear that your still doing good.

      Reply
    • Marc Profile Photo
      Marc

      Hello, my apologies for the late reply, but thank you all for the link and suggestions.
      Unfortunately the link to Nystatin cream 25g is no longer available. Should I just go ahead and purchase the 50g instead? I will go ahead and give Biom8 a try first since most you have much success with this as well. So glad to have ran into this forum…

      Thank You.

      Reply
      • Joakim Profile Photo
        Joakim

        Oh hi Marc,
        I cant tell if they mean that the 25 g nystatin cream is not available right now, or if they discontinued the product for good. If it’s the first case you might want to try it out before ordering a huge 50 g container. After all, since Michael posted my advice 1½ years ago or so, the feed back has been mixed. For some it seems to have worked wonders, while actually causing problems for others (some people have mentioned no effect and a sudden acne problem).

        If the price is not out of this world and you are eager to try, then go ahead and order the 50 g. I’m about to finish my second 25 g tube ever since I started using the cream 1½ years ago, so a 50 g tube will last you a good long while if it’s effective! 🙂 Don’t order more than one tube, though, as they also have a shelf-life or a ‘best before’ date.

        Otherwise, Biom8 seems to also get a lot of good feedback. Maybe you should try that first? It’s an all natural remedy, so if it is effective for you, you avoid using drugs, which is always preferred I guess 🙂 Then you can come back for the nystatin, if it isn’t. Maybe by then they have more 25 g tubes.

        All the best,
        Joakim

        Reply
  20. Marc Profile Photo
    Marc

    Hello, my name is Marc and I’m a long time SD sufferer, and just like everyone here on this site, I’ve tried everything. Jumped from derma to derma hoping that one might have the answer to all of my questions, but most of all a medication that can stop SD. If it’s not to much of a troubled to ask, can someone please point me to the right direction where I may purchase BIOM8 and Nystatin creme. Willing to try anything that might have every possibility of curing my SD. Please Help!!

    Reply
  21. Marc Profile Photo
    Marc

    Hello, my name is Marc and I’ve had SB for almost 5 years now. This is my first time here on this site and it seems promising. I’ve been to a lot of sites over the years trying to find a solution to my SB condition, but always ends on a dead end. Today I had a flare up and wanted to search online hoping someone might have a new solution to what I’m experiencing. Currently having problems controlling SB on my eyebrows, and it causes my eyebrow hair to fall off every time I get a flare up. Can someone please point me to get right direction as to where I might purchase Nystatin cream. I tried searching on amazon but I wasn’t able to find one. Thank You!!

    Reply
  22. Riley Profile Photo
    Riley

    Hi Michael, I wanted to report in!

    I’ve been using topical steroids on my face (I know, I know..) because my condition got so unmanageable again. I also used the cetaphil lotion/face wash to keep things in check, while waiting for the biom8 I ordered from you. I received it without any problems but I didn’t have any flare-ups when I actually received it, so I waited until I did… which was 2 weeks ago.

    I tried your product for a week and half, and unfortunately it just made my seb derm a lot worse. I’d also ordered Nystatin from amazon DE after seeing your article here a while back, which is what I’m trying now.

    So far, I’m three days deep and it does seem to be making it go away, slowly but surely; not as quickly as the steroid I was prescribed, but I only want to use that for absolute emergencies now. I’ll report back again in a week or so regarding the Nystatin! Since the article mentions that Joakim’s seb derm was gone in two weeks, I’ll give the product that long until I revert back to using my last-ditch resort.

    Reply
    • Michael A. Profile Photo
      Michael A.

      Hi Riley,

      Thanks for the update. It’s unfortunate that the Biom8 didn’t clear the seborrheic dermatitis.
      It’s hard to pin-point why for some the results are so fantastic, while some users report no effects or even worsening.
      So far my most solid hypothesis has been that some individuals simply have either a different species of malassezia of fungus (immune to the specific fatty acids used in the formula) or a different bacteria/fungus all together.
      Some users have suggested that Demodex may be at fault for certain cases. Here is the comment thread that discusses this: Demodex Related Comment Thread.

      Hope that helps and that perhaps the Nystatin can provide you with some good results.
      Look forward to hearing how things turn out.

      Reply
  23. Ian Profile Photo
    Ian

    Just to continue with my updates here.

    My routine has been mostly similar to what I’ve been doing for the past month, with a couple minor changes.

    AM:
    As of the past week I now just occasionally use Michael’s BIOM8 Oil as a cleanser and mix it with shampoo in the shower. I didn’t notice results from using it as a daily moisturiser after several weeks, but it works just fine as a gentle cleanser so I continue to use it this way (better than throwing it away, after all). Then I use a simple light moisturiser with minimal ingredients (Sebamed Clear Face Gel) and that’s it.

    PM:
    I wash my face, and then apply Skinoren gel (15% Azelaic Acid) as always (can’t tell if it’s helping my SD at all but it helps my acne, so I’ll continue to use it). I used to apply Sebclair (aka Promiseb) cream at this stage, but I replaced it with a very interesting cream I found called Ducray Kelual DS Cream. Like Sebclair it has piroctone olamine which is an antifungal, but the interesting thing is that it also happens to have crotamiton, which I mentioned in a previous post was the ingredient used in a study to treat demodex mites. The fact that they included crotamiton lends further credence to my theory that a demodex involvement shouldn’t be entirely ruled out as a cause of symptoms that manifest very similarly to SD.

    Here’s the full ingredients list for the Ducray Kelual DS cream:

    Aqua, Caprylic/Capric Triglyceride, Cyclomethicone, Dicaprylyl Ether,Cetearyl Alcohol, Acetamide MEA, Glycolic Acid, Guandine Carbonate, Glyceryl Stearate, Plymethyl Methacrylate, Ceteareth-33, Crotamiton, Piroctone Olamine, Serenoa Serrulata fruit Extract (Serenoa Serrulata Extract), Tetrasodium EDTA.

    I don’t do raw honey masks anymore because they had no effect on my SD and were a pain to do. I’ve been wanting to keep my routine as simple and stress-free as possible and I’ve kept it that way, and have no intentions of doing otherwise anymore.

    As for results, if there have been any it’s been quite minimal. I think the sides of my nose might be *slightly* less pink, but it’s hard to say.

    But to echo what I said in my last post, I continue to suspect that I might have demodex involvement because my dermatitis appears to manifest itself a bit differently from the standard SD symptoms. Namely, from the photos and accounts of SD sufferers I’ve noticed that there’s this tendency towards concentrated patches of redness that look like flakey rashes. I would describe what I have as more of a diffuse pinkness across my central face (minus the forehead, which is completely clear) that gradually fades out towards my cheeks, and my nasolabial folds and chin crease are a bit redder than that surrounding pinkness. Basically, I always look like I have a mild sunburn.

    Therefore I want to rule out the possibility of demodex involvement. In the study I posted previously, they recommend using a 10% crotamiton cream/lotion for 2-4 weeks. The Ducray Kelual DS cream contains crotamiton (which could be why I’m seeing extremely marginal improvement, if any) but judging from its location on the ingredient list I’d say it’s only a fraction of the 10% concentration recommended by the study. There is a cream available OTC in the UK called Eurax that does contain 10% — I ordered it a while back but then I left the country for the holiday and didn’t receive it in time, but now that I’ve returned I’m going to start using it.

    So for the next 2 weeks I’m going to apply Eurax to my entire face morning and night. If I see improvement I’ll continue the course for an additional 2 weeks. If I don’t see any improvement whatsoever, then I at least have eliminated it as a possibility and can just focus on it being a case of SD.

    Michael, I’ll be sure to report back about my results after this trial. Interesting that you’re also encountering more research about demodex!

    Also interesting about that person who didn’t see results from the BIOM8 Oil, like myself, but noticed improvement from the Probiotic Spray. I’ll bear that in mind. I want to give this crotamiton trial a proper shot first, but if it doesn’t work out then I’d be interested in trying out the spray, because if it is indeed SD then I clearly need a different angle of attack. Beyond the Kelual DS cream I’m currently using and another cream I found that contains climbazole and piroctone olamine, I’ll be a bit exhausted for options on the SD treatment front if I end up having to return to it. I don’t suppose there’d be any discount available for those curious in trying out the spray after giving the oil a go with no results? No worries if not.

    Cheers and Happy New Year!

    – Ian

    Reply
    • Håkan Profile Photo
      Håkan

      Hi

      Here is a topical probiotic spray that looks very intresting:

      http://mist.aobiome.com/

      Only available in US and Canada.

      I think that in a lot of skin issues the skin is lacking from good bacteria to keep the bad bacteria at a low level.

      Creams like antifugals and steroids will kill the good bacteria and therefor never cure the skin in the long run.

      The ideal thing should be to optimise the gut health with healthy foods like the John Vale Skin clear programme. It’s free for download. And also use oil free topical probiotics.

      And here is another one designen for rosacea and acne that doesn’t kill good bacteria on the skin like steroids do:

      https://www.gladskin.com/en/

      No oils work for me. The oil free biom8 probiotic spray does not make my SD worse.

      The last weeks I have only washed my face with water when taking a shower. My face has improved by 50% from this.

      Will start the Skin clear programme later this month.

      Best wishes

      Håkan

      Reply
      • Michael A. Profile Photo
        Michael A.

        Hi Håkan,

        Thanks for linking that product. Definitely looks interesting. Let me know if you give it a try. If the bacteria used can actually convert urea into nitric oxide, it should potentially be very helpful for SD. The Biom8 Probiotic Spray contains arginine for this same reason. However, the specific probiotics used serve a different purpose.

        In terms of creams and topical products not really being a solution, I do partially agree. This was my thinking for quite some time. Obviously humans shouldn’t need to really on externally applied things in order to be healthy. However, todays environments and food choices/availability seems to have impacted many levels of human health and immunity.

        Plus my experience with how well Biom8 has worked for me has impacted my opinion as well. Perhaps a topical that can help you regain control of your skin and allow you to slowly focus on rebuilding all other aspects of the immune system free from stress (caused by SD) can be crucially beneficial. Most of my research has pointed to the fatty acid as being one of the key aspects of seborrheic dermatitis, thus I think modifying the sebum’s composition is pivotal to long term results. However, everyone is different and as long as we all share our experience I believe we can create a solid foundation of knowledge for others unfortunate enough to travel down the same path.

        Look forward to hearing how the program goes.
        Best of luck!

        Reply
    • Simon Profile Photo
      Simon

      Hi Ian,
      As it happens, I’m also experimenting with Skinoren gel and Kelual DS Creme right now after an (short) unsuccessful trial with BIOM8 Oil. For the time being I decided to leave the Kelual out to see what the skinoren gel does on its own. So far I would also say that it helps with pimples but not so much with the SD scaling and redness, but it is still too early to definitely tell.

      I tried out the Kelual Creme in addition for some days which didn’t seem to make much of a difference. But this was not an adequate treatment period. I recognized though that the Kelual has a tendency to try out the skin, a little bit like the Skinoren gel. This was also a reason why I decided against using both compounds together.

      With regard to this Demodex theory that you referred to: I think for myself I can pretty much rule that out. I applied a whole tube of Soolantra Creme (Ivermectin) over several weeks onto the affected areas of my face but had no positive results from it. But let’s see what turns out of your Eurax experiment.

      Reply
      • Simon Profile Photo
        Simon

        Hey Simon,

        Wow, then we’re in quite a similar boat! I’m definitely a fan of azelaic acid in terms of treating acne, though I was hopeful that it’d have more of an effect on my SD seeing as some research points to it being helpful in that regard. Scaling hasn’t been much of a problem for me (for all I know the azelaic acid could be the reason why?), but my primary concern has always been the redness and it hasn’t had any noticeable effect on that. That said, the way I see it, it helps my acne and at least doesn’t appear to be aggravating my SD (which I worry might be the case if I were to use other, more irritating acne treatments like Retin-A), so I’m going to keep using it regardless.

        It’s understandable that a combination of azelaic acid and the Kelual DS creme can be a bit too drying, as the latter contains a decent amount of glycolic acid. I noticed that myself when I’ve been using the two together. I tried a “treatment phase” of the Kelual DS creme, using it both morning and night for 2 weeks (as is suggested on the manufacturer’s website), but now Intend to just use it twice a week and only at night. On those nights I’m thinking that instead of using the Skinoren and Kelual together I’ll just use the Kelual, to minimise the dryness/irritation.

        Sorry to hear that the ivermectin cream didn’t have any positive results for you. I’m not getting my hopes high that crotamiton will be my saviour, as promising as the results of that study are, but I want to at least go through a proper treatment course of it as otherwise it’ll always be nagging me in the back of my mind. Moreover, giving it 2 weeks isn’t much of a commitment — I was willing to do the same trial period for antifungal creams like the Nystatin but, unlike those creams, the crotamiton cream doesn’t appear to have any problematic ingredients that will almost assuredly clog my pores and wreak havoc on my face!

        Reply
        • Michael A. Profile Photo
          Michael A.

          Hi Guys,

          Just downloaded a bunch of research papers on azelaic acid and the first thing that jumped out right away:

          Azelaic acid is available currently as a 15% gel approved in the United States for the treatment of rosacea. It is a 9-carbon dicarboxylic acid obtained from cultures of Pityrosporum ovale.

          Pityrosporum ovale is a different name of malassezia, the fungus most commonly documented as the culprit behind seborrheic dermatitis. Haven’t read much else, but this just jumped right out at me. Will update once I actually read some more of the papers.

          All the best.

          Reply
      • Michael A. Profile Photo
        Michael A.

        Hi Simon,

        Sorry to hear the Biom8 didn’t work out for you.

        One thing that I just hypothesized, is that potentially the products that may be helpful in acne might be negatively impacting the skins protective barrier. Thus, allowing the bacteria activity to cause inflammation and disruption of the skins normal cycle. Will see if I can research this hypothesis further and update you guys on any potential findings.

        Look forward to any updates.
        All the best.

        Reply
    • Michael A. Profile Photo
      Michael A.

      Hi Ian,

      Thanks for the detailed update. You seem to have a good and well thought out approach. Really interested to see how things turn out.

      As for the oil not working for you, it does seem like it stems from that fact that your issue may be caused by a different fungal strain, microorganism or potential demodex themselves.

      That cream you mentioned (Ducray) seems to have fairly promising ingredients. Thanks for brining it to my attention.

      As for the discount. Definitely not a problem. Just message me via the contact form and will send you details. 🙂

      Hope you finally find some relief.
      Have a great 2016!

      Reply
  24. Håkan Profile Photo
    Håkan

    I promised myself to stop putting oils to my face, but just had to try borage oil on my eye lids and in between my eyes yesterday.

    My skin looked great from the moment I put it on and still does after 20 hours!

    If the John Vale Skin Clear programme does not work I will try borage on the rest of my face.

    Merry Christmas

    Håkan

    Reply
  25. Vincent Profile Photo
    Vincent

    Hi, I have seborrheic dermatitis on my scalp for a year now and have tried all sorts of products and nothing really helped. I’m thinking about trying Nystatin on my scalp, but I read on the internet that several people who use Nystatin are experiencing hair loss from it. Mostly these people use it to treat other conditions. Do you notice any hair loss?

    Reply
    • Joakim Profile Photo
      Joakim

      Hi Vincent, no Ii do not experience any hair loss. But then again I don’t apply any of it to my scalp, so that would be weird.

      Nystatin might come in different concentrations, I’m not sure, so if you can, note the concentration of the nystatin when you read stories regarding hair loss. It could be that the type used in those cases is more potent than the one recommended here.

      Best regards,
      Joakim

      Reply
      • Nic Profile Photo
        Nic

        Hi Joakim, before using Nystatin, did you have eyebrow hair loss along with wet/dry dandruff? I’m experiencing that, and hopefully Nystatin can help me out with the hair loss especially.

        Reply
        • Joakim Profile Photo
          Joakim

          Hi Nic,

          yeah, I definitely had SD under and around my brows, so plenty of redness and dandruff. But I don’t recall that I had anything that I would characterize as eyebrow hair loss. I mean, I regularly lost eyebrow hairs – and still do – but nothing to an extent where I’d have bald patches or so. Just your everyday shedding, I guess.

          Reply
  26. Patricia Profile Photo
    Patricia

    I am new to this site, saw it first about two weeks ago.I am currently awaiting the Biom8 oil, while basically trying out coconut oil on my sd, which is on my scalp, in back from about middle of my head down to where my hair ends. It been such a pain, fir so long. I have long curly hair, so its not visable, but is sooo uncomfortable.
    i have been to dermatologists all my life, who just give the same old advice, shampoos that,while they may have ingredients to quell the sd, they wind up leaving my scalp feeling burning, tight, itchy and irritated. I am now on my own personal quest fir natural solutions….seems that maintenance is all I can expect. Maybe a cure? So far, I am feeling a pretty decent relief by using pure coconut oil.
    There is a doctor in New York City, (i live 25 mikes away) Dr. Ash, who is an integrative type doctor, who says, on his website that he prescribes Nystatin for SD. I am interested, but have not yet checked this out with a doctor yet, as i believe it must be prescribed, not over the counter. I wonder, for thosee of you using it, how do you know what strength to use, or how many times to apply, in order to kill the fungus, but not cause skin chaos? I am quite excited to try it, because if its even a temporary type “cure” wow, I ll be forever grateful

    Reply
    • Joakim Profile Photo
      Joakim

      Hey Patricia,

      I guess your doctor would instruct you to use it in a way, so you don’t over use it. I was prescribed 4 tubes to be used over 2 years. That should be more than plenty. I’m a year into treatment — still SD free (although with 1 or 2 relapses) — and I’m still on my second tube, which has plenty left.

      It says on my prescription that I should use it once daily, but I’m quite sure that my dermatologist suggested that I could use it twice if I was having a rough time. For me it has never given me a burning sensation similar to those nizoral shampoos for instance. And when I’m clear of SD I tend not to use it — during summer for instance.

      I think someone else asked to the specific creme somewhere else in the comments, so you should be able to find it and instructions on how to order it from Germany, if you don’t want to see a doctor about it. I don’t know if that is expensive in the US.

      Best of luck, though, I hope you see some nice results either from nystatin/biom8/or whatever proves to be your solution 🙂

      Reply
    • Joey Byrd Profile Photo
      Joey Byrd

      My sd is completely gone since my last post. I suffered for years and nothing worked. Nothing. Applied nystatin for two weeks twice a day and washed with selenium sulfide shampoo. Gone, gone ,gone ,gone, thank God almighty! It’s gone. Try it. It works

      Reply
      • Joakim Profile Photo
        Joakim

        Hahaha, success stories make me so happy! I’m so happy for you – that you are finally rid of it. And it reminds me that I was not always SD free. I’ve almost gotten used to it by now, but this takes me back to the feeling I had when I first got rid of it.
        Enjoy your new face and look forward to forgetting that it was ever different! 😉

        Reply
  27. Håkan Profile Photo
    Håkan

    Tried Nystatin. Just made my skin more flaky. Tried raw honey. Made my skin so much red.

    The biom probiotic spray is the only thing that does not make my skin worse.

    After new year a will complete the clear skin programme. You can download it for free http://www.juicemaster.com/clear-skin-programme/

    I rather do something for real than to keep looking for answers and traying topical solutions that don’t work.

    Have a great weekend all

    Håkan
    Sweden

    Reply
    • Michael A. Profile Photo
      Michael A.

      Hi Hakan,

      The clear skin program looks promising and will likely have very good results. With time though, it appears the best approach is one that you can easily integrate in your daily life. Juicing was just something that I’ve been too lazy to be consistent with. Currently, I just make sure to eat a certain amount of raw vegetables every single day, drink lots of water, exercise and all the general good stuff. However, I’ve also been using the Biom8 pretty much every single day, so hard to say if it’s doing all the work.

      How have things progressed since? Any updates on the Probiotic Repair Spray usage?

      Hope you can finally find something that resolves things for you. Still busy compiling research and expanding the work. Will update if I find something that may be useful/applicable to you.

      All the best and happy holidays!

      Reply
      • Håkan Profile Photo
        Håkan

        Hi Michael

        The probiotic spray is great since it does not make my face worse. I find it important to always wash my face before using it.

        I’m having a break from putting anything on my face a few weeks now. Except for borage oil on eye lids which works great.

        The John Vale Skin clear programme is not just juicing. The 30 day programme consists of soups and sallads with chicken and salmon as well.

        I will be starting it on January 4th. Will come back with results.

        Happy holidays

        Håkan

        Reply
        • Michael A. Profile Photo
          Michael A.

          Hi Hakan,

          Thanks for the update and the tip on the Probiotic Repair Spray usage.
          Is the borage oil only working for the eyelids?

          Look forward to hearing your results from the John Vale program.

          Hope you enjoyed the holidays!
          All the best!

          Reply
  28. Ben Profile Photo
    Ben

    Hello Joakim,

    My Seborrheic dermatitis is almost exclusively and primarily on my eyebrows. I was wondering if you used the Nystatin cream on your eyebrows as well, and whether the cream was alright to apply on your brows, without clogging the follicles or making the hair very greasy?

    Kind regards, a fellow Scandinavian with SD.

    Ben

    Reply
    • Joakim Profile Photo
      Joakim

      Hi Ben,

      I find that I have SD pretty much everywhere where I have hair on my head. Hair, beard, eyebrows, everything. The scalp got better, as I wrote in the story above, just by applying nystatin to my face and using shampoo with zinc pyrithione. However, I also apply it to the spots in my beard and eyebrows that are affected. It’s usually the same places, where it keeps coming back if I don’t treat it. So yes, I’d say that you can use it in your eyebrows without any adverse effects. Just be careful not to put it in your eyes by mistake 🙂

      I haven’t experienced greasy hair or clogged follicles, but apparently some of the other guys have concerns regarding the isopropyl myristate that is in the creme. So just be warned, if you have also had bad experiences with that ingredient. In my opinion, however, it is really not a very oily/greasy creme.

      Best of luck!

      Reply
  29. tj Profile Photo
    tj

    Hello,
    I ordered nystatin from Amazon.de.
    It has been 2 months that I am applying it on my face. I tried almost everything suggested and finally I am cured with nystatin, not only my face but the cheast and sculp too. But it caused acne problem on my chin similar to Ian’s but compared to sd it is not effecting my social life that much.
    I applied it once a day on my face and it helped with the other spots as well. So I have this idea now, I will start applying not on my face but other spots effected before, to see if it will keep my face cured.
    I will let you know when I have results.
    Thank you for this community.
    Regards,
    Th

    Reply
    • Michael A. Profile Photo
      Michael A.

      Hi TJ,

      Hope all is well. Just wanted to chime in.
      Not sure where you are located, but I believe you may be able to obtain a custom formulation of nystatin cream from your local pharmacy.

      Let me know if you pursue this idea.

      Happy holidays and hope you have a wonderful 2016!
      Best of luck.

      Reply
      • tj Profile Photo
        tj

        Hello Michael,

        I trust you are doing well.

        Thank you for your suggestion. I live in Istanbul Turkey and here we only have nystatin for oral use. But if you think that it helps to reduce acne, I will try to get help from Germany with custom formula.
        I tried not to apply nystatin directly on face but this time the risk of sd appeared which I never want to face again.
        I hope I can find a way to have it in Istanbul.

        Thank you,
        tj

        Reply
        • Michael A. Profile Photo
          Michael A.

          Hi TJ,

          Everything is good with me.
          Hopefully you can find it in your area. Let me know how things turn out (might be useful for other readers who happen to be from you part of the world).

          All the best.

          Reply
          • tj Profile Photo
            tj

            hey michael,

            Unfortunately it is not possible to obtain custom formula of nystatin here. I would appreciate if you could tell me more about the ingredients of this formula. And I try to search more deeply.

            Kind regards,
            tj

          • Michael A. Profile Photo
            Michael A.

            Hi TJ,

            Unfortunately, haven’t used any Nystatin creams so can’t really comment on a good combination of ingredients.
            Regardless, the more minimal the ingredients list the better. Nystatin is basically all that is needed, while the other ingredients simply provide a base to hold the active ingredient.

            Hope that helps mate.
            Best of luck.

        • Joakim Profile Photo
          Joakim

          Hi TJ.

          I just did some digging in the comment section and found this:

          >For anyone else looking, the ingredients list seems to be the following for the Nystatin >Lederle Cream:
          >Nystatin 2.2%
          >Cetyl stearyl alcohol (vegetable)
          >Water, purified
          >Sodium hydroxide
          >Isopropyl myristate
          >Polyoxyethylene (20) monostearate
          >Sorbic acid
          >Glycerol 85%
          >Lactic acid

          I don’t know if you can have this custom made in Istanbul. It sounds like you are using an oral formulation? I don’t know how that would work at all, but if you are achieving results, then nevermind! 🙂

          Also, if you want to try to order it from Germany, here’s what has been suggested before. You can check whether it is also available to have shipped to Istanbul.

          All the best!
          Joakim

          Reply
          • tj Profile Photo
            tj

            Hi Joakim,

            Thank you for your all inclusive explanation.

            I have ordered 2 boxes from amazon.de. In istanbul there is only oral form.

            It is better to have less ingredients as mentioned before because of the possible effects of the others like Isopropyl myristate which causes acne. So this idea came up if it is possible to have custom made nystatin without Isopropyl myristate but unfortunatelly it was not possible since now.
            Anywat at least i don’have sd right now which makes me feel good and i don’t need to apply it daily so acnes don’t show up frequently. i wiil search deeply in one of my visits to europe.

            Kind regards,
            tj

          • Riley Profile Photo
            Riley

            Hi all, updates on my Nystatin experience!

            I think if you gave in early like me and started using steroid creams, Nystatin won’t work. At least, that seems to be the case for me.

            Nystatin was pretty much my last hope for a non-steroid solution, but perhaps my mistake was using it after I’d already used steroid cream. But I’ve cycled through all the holistic and medical treatments (minus Nystatin) before using the dreaded steroid cream, and it’s the only thing that didn’t seem to aggravate my skin further and actually make it better. I guess YMMV, really. My skin may just be addicted to it by this point, even though I use it very sparingly (one to two applications per week, at most). But still, I very much appreciate the work Michael has put into researching this condition, and I’m glad that biom8 is working for some people since it’s significantly less harsh than the cream! I hope the Nystatin and/or the other solutions work for you all, and thanks so much to Michael for all the research he’s put into this site!

  30. Hakan Profile Photo
    Hakan

    There is hope when creams don’t work and anyhow they won’t work when the body doesn’t get what it needs. And some creams will irritate the skin.

    Seb derm sufferers have cleared by following the free protocol on howtobeatpsoriasis.com. No one has come back after three months on the program, and said it doesn’t work.

    The thing is most people don’t manage to complete the program. Going from a regular diet to only eating vegetables and fruits for months is very challenging. But you can always eat more of them to not loose calories. Then try to add back foods one by one and see what foods you can handle.

    Someone will probably say that they have a friend who is vegetarian but has skin problems. But they forgot something. You have to stay away from processed food also. Sugar comes from plants but is processed. Wheat flour also.

    There used to be a seb derm group at yahoo managed by someone called steve with email canwegoplease2000@yahoo.com. This group cleared members with a diet of fruits and vegetables as well. A whole plant based food.

    Read more on the many health benefits of whole plant foods on nutritionfacts.org which is the most amazing health site on the web. It’s run by doctors on their free time specialized in nutrion. They go through thousands of research papers and present the most relevant info on their site. It’s not connected to the medicin industry or other intrests of money. They just want you to be healthy.

    Research say that we have eaten whole plant based foods approx. 90-95 % during the thousands of years we have developed, so that would make some sense. Now add alcohol, sugar, multi resistent bacterias in meat, other chemicals, GMO and so on.

    This will make it hard for us that probably have genetic issues as well.

    Professor Jane Plant has written several books on how to treat cancer with plant based foods. She almost died from cancer before changing here diet. I saw a documentery on TV where a man cured him self from cancer after reading one of here books on prostate cancer.

    This food gives the imune system enough strength to get us well again.

    I myself have not managed to manage the diet. But I think the key us to take it step by step, and not all in at once.

    Best wishes

    Reply
  31. Shane Profile Photo
    Shane

    Hi Guys,

    I ordered 3 packs of Nystatin Cream from Apons and received the order here in Ireland today. But they sent me Paste not Cream!!! I know for sure I ordered the Cream not Paste, because I ordered the cream in Oct and when I ordered this time I accessed the product from my previous order which arrived correctly.

    I emailed them and outlined the problem, but I know they’ll say I selected paste bla bla bla and therefore they won’t take it back. So my question is. Whats the consistency of the paste?? will it dissolve in my skin like an ointment?? I don’t want to open it incase by a small chance they take it back but if they don’t. Can I use the paste normally?? Otherwise its 3 bottles, complete waste 🙁 Thanks guys!

    Reply
    • Joakim Profile Photo
      Joakim

      Hi Shane,

      I have no idea about the paste. Hopefully they will take it back. What happened to “The customer is always right”? 🙂

      Maybe someone else has some experience with the paste.

      Best of luck,
      Joakim

      Reply
  32. Ian Profile Photo
    Ian

    Hey everyone,
    I received my order of Nystatin cream from Germany today, so I’ll keep you guys posted on how it works after a week or two. Will be using it once or twice a day. I figured the more experiences we share here, the more collectively informed we can be about possible treatments. Sorry to hear that Jay’s experience with it so far has been disappointing.

    I also ordered the BIOM8 oil, which I intend to incorporate into my routine when I receive it. Between that and Nystatin I’m hoping there will be a noticeable improvement soon. I figured this would be a good combination in the sense that I’ll use the BIOM8 oil on a regular basis all over my face, whereas I’ll concentrate the Nystatin cream on just the problem areas (since I don’t want to apply a fairly thick cream all over my face).

    Here’s some background on my situation:
    I’m 31, male. I’ve been a long-time sufferer of persistent mild-moderate acne since the beginning of my 20’s (my only concern in my teenage years was a blackhead-ridden nose so I thought I had dodged the acne bullet, but boy was I wrong). While I was studying at uni in the US I went on two 6-month courses of Accutane (at the standard dosage), spaced out by a few years, both of which only managed to temporarily clear it up. Then I discovered the regimen promoted at acne.org (where you apply an overly generous amount of benzoyl peroxide all over your face twice a day). The acne.org regimen didn’t clear me up entirely, but kept me clear enough that I stuck with it religiously for a good 5 years or so. However, it left my skin feeling constantly dry and raw and I wasn’t satisfied with how its effects continued to fluctuate so much, so I went off of it, suffered with some pretty nasty breakouts until I eventually settled into an alternative routine that’s a lot gentler and doesn’t involve heaping an inordinate amount of benzoyl peroxide on my face (now I just use Epiduo gel, which is a mixture of benzoyl peroxide and a retinoid and can be applied as just a pea-sized amount nightly). My acne still pops up much more regularly than I’d like but at least my face isn’t the active volcano that it was at the beginning of the year shortly after quitting the BP regimen.

    These past few years I was noticing some flakiness on the sides of my nose. I initially attributed this to the dryness caused by my constant benzoyl peroxide use, but even after making it a point to avoid that area when I applied the BP, the flakiness persisted. Jojoba oil was useful to control the flakes, so it never bothered me much. However, a little over a year ago these areas have gradually become much redder, oilier, and even itch pretty badly at times, and over the past few months it’s reached a new high and I’ve become very self-conscious about it. There’s also a very small pustule on the side of my nose, which I initially thought was just a run-of-the-mill pimple, yet it’s stuck around for 10 months now. If I extract it, it simply comes back. If I leave it alone, it crusts over and flakes off, stays red, and then comes back. It’s like it’s stuck in a time loop. That’s when I realised that what’s happening around my nose isn’t acne but some kind of persistent infection that simply wasn’t resolving on its own. So I spent my 20’s suffering from acne and I’ll get to spend my 30’s suffering from acne AND seb derm? Oh joy.

    The reason I mention my constant benzoyl peroxide use following the acne.org regimen is that I noticed that shortly after quitting it at the beginning of this year, my face has started producing an extreme amount of oil. I’ve always been a bit shiny-faced (the only positive being that it means I’m often told I look considerably younger than I am) but now it’s ridiculous. 15-20 minutes after washing and the oil returns in full force until I look like I’m sweating from a heavy workout. I don’t know if my many years of BP overuse have caused this, or if they simply hid the problem because I was routinely drying up my face with so much BP (I did moisturise after each application but my skin sucked up all the moisturiser, I’m guessing because the BP dried it out so much that it needed it). Either way, there seems to be a pretty direct correlation with my face’s excessive oiliness and my seborrheic dermatitis because I noticed where I suffer from it is even oilier than the rest of my face.

    I’ve tried many topical treatments (primarily antifungals as I’m trying to avoid corticosteroid creams), but if I don’t find a solution soon I’ll be at my wit’s end and feel compelled to ask for a prescription for a third round of Accutane (albeit this time on a much lower dose spread out over a longer time, which appears to be a lot more common here in Europe) to control this trifecta of oiliness, seb derm, and acne.

    So the things I’m trying now are:
    1.) Azelaic Acid 10% applied all over the face once a day — seems like a particularly wise choice in my case because azelaic acid appears to be one of the few topicals that can treat seb derm AND acne at the same time with supposedly good results. It’s still too early to tell if it’ll have an effect, though.
    2.) Nystatin cream applied only to the problem area once/twice a day.
    3.) And when I receive the BIOM8 oil it’ll be applied all over the face right after my morning shower.

    As I said I’ll let you know the results. I’m giving it till the end of the year to see if there’s at least some improvement. Then I’ll ask if I can get an oral antifungal. If I ultimately end up going down the low-dose Accutane route, I’ll let you know the results from that as well. I’m pretty fed up, all in all. If this seb derm issue had been my first face problem since adolescence I’d probably have a lot more patience with it, but since it’s coming off the top of a decade-long struggle against acne I feel pretty emotionally drained. -__-

    Reply
    • Joakim Profile Photo
      Joakim

      Thanks for the thorough background, Ian. I also had a lot of blackheads when I was a teen. I actually don’t know what they are made from, but I guess they are also some lipids/oils/whatever that can feed the fungus. There might be a correlation, but what do I know.

      I don’t know what else to say but hang in there. I’m looking forward to hearing your results and I’m crossing my fingers, but after Jays bad experience I’m less optimistic. Hopefully you will have a success-story on your hands in a few weeks. Otherwise it might be interesting to look into the whole input/output thing: What you eat and what in turn comes out your skin. I’m not sure how — Michael is the local expert on that, I guess — but it should be possible to reduce the production of oils and sebum by diet and lifestyle changes.

      Anyway, we’ll deal with that if it comes to that 🙂 For now I wish you the best of luck with your new regimen! Let us know how you do.
      Best regards,
      Joakim

      Reply
    • Ian Profile Photo
      Ian

      Have been using Nystatin cream once or twice daily since I received it 5 days ago. As I suspected, in accordance with past experiences using creams to treat that area my acne-prone skin hasn’t agreed with it and I have a cluster of pimples on the sides of my nose where I’ve been applying it. This likewise happened when I was using a ketaconazole 2% cream (Daktarin Gold). I can’t tell if there’s been any improvement with my SD because the redness associated with SD has now been replaced by redness associated with acne. 🙁

      At any rate I’ll continue applying for at least a few more days, though chances are that it’ll continue to exacerbate my acne breakout. I suspect that the thickness of the cream is clogging my pores, and there’s no way that my skin would just get used to that — the problem will continue for as long as I keep using it. Would potentially be great if it were in a gel vehicle, and in fact I don’t understand why antifungals are almost exclusively in creams since SD and acne can be concomitant issues.

      At least I was prudent enough to be applying the Nystatin cream only around my nose — had I been applying it all over I might be dealing with a full-blown breakout at the moment.

      I have higher hopes for the BIOM8 oil because being a lightweight oil I doubt it’ll aggravate my acne. I’m also intending to use azelaic acid indefinitely as it’s one of the few topicals that can treat both problems. It’s early days for using both (less than a week), but I’ll be sure to update here further down the road!

      Reply
      • Ian Profile Photo
        Ian

        I actually managed to pinpoint the ingredient responsible: isopropyl myristate. It’s in a lot of antifungal creams and unsurprisingly I just discovered that it’s in the Nystatin cream I bought from Germany as well. Unfortunately it’s known to be an extremely comedogenic ingredient, one of the biggest offenders since it’s so commonplace.

        So sadly I’m going to have to stop using the Nystatin cream. :/

        If anyone is interested in buying it off of me on the cheap, let me know, since it’s either that or it’s going in the rubbish. I used it for just 5 days so it’s almost a full tube’s worth. (I’m in the UK, by the way, so bear that in mind).

        Reply
        • Jay Profile Photo
          Jay

          Hi Ian – sorry I didn’t check in before and see your post regarding acne & SD.

          As you’ve already pointed out, Isopropyl Myristate is a horrible ingredient for anyone who is acne prone. We had a quick look over the ingredients further down the comment thread and I pointed this out as being a massive irritant for those with sensitive skin – it’s definitely a shame as other people have had great success with the Nystatin!

          The Azelaic acid should hopefully be beneficial to both the SD and acne. It seems to work for a variety of reasons: “Studies confirm antimicrobial properties, sebosuppressive activity, anti-keratinizing activity, anti-inflammatory and immunomodulatory effects and antimycotic activity — including specific activity against Malassezia”. But as with everything some people find it a god-send cream and others find it just worsens their condition; hit and miss as always.

          Let me know how you get on with the BioM8 oil as it’s something I’m keen to try, but at the moment I’m having to try out cheap remedies due to Christmas & helping out my parents with a couple of things. Also interested to see your experience with AzA (15% tends to be one of the most effective, but I’m unsure if various formulations will have differing ingredients that cause irritation), as I have a tube of Finacea lying around which is good until 2016 and I might be persuaded into trying that again.

          I’d also like to touch on the anti-fungal and Accutane route as something that might help you. Whilst I don’t have any experience with the anti-fungals, they’re extremely cheap to try (Fluconazole can be bought on Amazon for around £1 per tablet and I believe you can use it once a week for maximum efficacy with minimal to no side effects) and this should at least give you an idea if any of your skin issues are fungal in nature. In regards to low-dose Accutane, I have a lot of experience with this, I was on 10mg every other day for 6 months, then dropped to 2 x 10mg a week and I was virtually clear of all acne symptoms, did nothing for SD though and sebum remained on my nose… Could be because my dosage was extremely low, but I had very few side effects aside from slightly dry lips (easily manageable) and occasional loose stools, but that could be because I was constantly altering my diet.

          But I’m keen to try out as many other things as possible before I resort to conventional heavy-duty treatments!

          Let me know how things go – wish you all the best with the skin 🙂

          Jay.

          Reply
          • Ian Profile Photo
            Ian

            Hi Jay,

            Thanks for the response. It’s helpful to hear from someone else who’s in a somewhat similar boat (having suffered from SD and acne), so my adverse reaction to Nystatin feels less unusual.

            It’s been about a week since my last update. I quit use of the Nystatin (unsurprisingly) and have been using Michael’s BIOM8 oil every morning after showering, and every night I apply Skinoren gel (which is 15% azelaic acid — I mentioned in the previous post that I was using an over-the-counter 10% azelaic acid lotion but I quickly decided to upgrade to a higher strength gel-based formula with fewer ingredients). I apply BIOM8 and Skinoren to my entire face, and follow up with Sebclair which I apply only to my nose creases (I replaced Nystatin with Sebclair because as far as I can tell Sebclair isn’t clogging my pores).

            At the moment I’m cautiously optimistic. The erythema on one side of my nose has been very gradually lightening up, but the other side of my nose is still quite red because there’s a deep and fairly large under-the-skin pimple hanging around (which I suspect my earlier use of Nystatin is responsible for). In the areas where I do see improvement it’s difficult to tell if that’s because I’m actually managing to fight the SD, or if it’s simply because my acne-prone skin is being given a chance to heal now that I’ve stopped using Nystatin. Only time will tell — it’s early days yet.

            I’m hopeful that azelaic acid will treat my SD, but even if it doesn’t, I’m still going to keep it as a mainstay in my routine because I’ve been looking for an anti-acne substitute for benzoyl peroxide for a while now and think I’ve finally found it. Azelaic acid is more versatile, gentler, doesn’t bleach fabric, can reduce sebum production (albeit slightly), and treats post-inflammatory hyperpigmentation — it’s a no-brainer to replace BP with it on the acne-fighting front and relegate BP to just spot treatment.

            Thanks for sharing your low-dose Accutane experience. It’s still on the cards as a last resort, though I’m aware it might not help the SD. I know the general guideline is to avoid using any harsh topicals while on Accutane but this seems to be mainly a concern for those on a standard dose, so I’m curious if being on such a low dose would open up the possibility of combination therapy (i.e. being able to continue using azelaic acid so long as my skin doesn’t find the combination of that and Accutane too drying).

            Cheers!

          • Ian Profile Photo
            Ian

            Another update:

            What I’ve been doing:
            1.) Adding a single pump of BIOM8 oil to my moisturiser once a day, to entire face
            2.) Applying Skinoren (azelaic acid 15%) every night, to entire face
            3.) Following up with Sebclair cream, applied only to affected areas (sides of my nose, crease on my chin), morning and night
            4.) Applying 90% raw honey mask/10% distilled water mask to entire face for 3 hours every other night (as per this study: http://www.ncbi.nlm.nih.gov/pubmed/11485891). I’ve been doing this for almost a month at this point, and will continue it on a weekly basis for another 6 months as the study suggests.

            The positives:
            I no longer have a bunch of clogged pores around my nose so I can say with absolutely certainty that the Nystatin cream was responsible for that, having stopped using it about 2 1/2 weeks ago. Also, the azelaic acid has been doing a pretty good job of keeping my acne in check (which is one of the reasons I’ve been using it), so I’m happy that I no longer have to use benzoyl peroxide at all at this point, after 5+ years of being so heavily reliant on it and suffering its drawbacks.

            The negatives:
            While progress on the acne front has been great, progress on the SD front has been painfully slow, especially considering I’ve been very strictly following a routine in which I’m attacking it from three angles (coming up on almost a month of these raw honey masks, and having used both BIOM8 oil and Sebclair consistently for over 2 weeks). Unlike acne, which I’m more than aware can take at least a couple of months to respond to a new treatment regimen, I’m under the impression that SD symptoms should respond in 2-4 weeks.

            I’ll continue my current regimen regardless, probably for a fairly long time. My reasoning being that a.) slathering honey on my face every other night for the past 4 weeks has been a massive pain, but doing it for the next 6 months on just a weekly basis as per the study’s recommendations is a lot more manageable by comparison, b.) with the BIOM8 oil and Sebclair, even if they don’t end up doing much for my SD at least they also serve as moisturisers that don’t clog my pores, so they’re not doing any harm, and c.) I’m going to be using Skinoren indefinitely because it addresses my acne and post-inflammatory hyperpigmentation (I’m an azelaic acid convert at this point).

            As I’ve been a bit frustrated with the slow response, if any, on the SD front I’ve been looking into how I can rule out the possibility of it being something else that manifests itself similarly to SD, and I came across this study about demodex dermatitis: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958185/
            It mentions that demodex dermatitis symptoms can look an awful lot like SD but argues that it should be considered a separate condition. The subjects applied crotamiton cream to the affected areas twice daily for 2-4 weeks and the response rate was impressive — but what I find particularly interesting is that subjects responded very well to it even though some tested negative for a high demodex concentration on their face. They recommend crotamiton if you’ve been unimpressed with the results of other SD treatments (which at this rate might end up being the case for me).

            Crotamiton is sold OTC in the UK as Eurax cream, so I’ve ordered a small tube. I’m not getting my hopes too high, but I want to give it a shot so I can at least rule it out if it doesn’t end up working. Moreover, it doesn’t contain the extremely pore-clogging isopropyl myristate (hooray!) so it shouldn’t do any harm. If I don’t notice improvement after 2-4 weeks then it’s reasonable to conclude that it’s not treating it.

            Will post more updates further down the road.

          • Michael A. Profile Photo
            Michael A.

            Hi Ian,

            Interested note regarding the Crotamiton. Have been adding this topic to my research lately, will update once I have more information compiled. Did you end up trying this out yet?

            PS> Also have a bit of research papers on acne, perhaps these may be useful to you. Will somehow send over via email.

            All the best.

          • Michael A. Profile Photo
            Michael A.

            Hi Jay,

            Just wanted to chime in on the Isopropyl Myristate and Nystatin. If I’m not mistaken, you could get a custom formulation of Nystatin cream from your local pharmacy. At-least this is how it works here in Canada. Nystatin is one of the most commonly used anti-fungals, so it really shouldn’t be a problem. Perhaps you could even get it in a water based solution.

            As for the hit and miss, this seems to apply universally 🙂

            Happy holidays! And best wishes for the New Year!

    • minlo Profile Photo
      minlo

      Hi Ian,

      I swear man you’re experience is like a carbon copy of mine. I too had acne when i was 17 , started using clean and clear wiped with salycilic acid as active ingrediant then a glycolic acid cleanser.
      I recall very well this one time , my forehead didnt at all have acne it was clear ans smooth started cleansing that part once a day with the cleanser and then i started getting acne there and now i have SD there as well as on mine cheeks.
      Here is the thing also i too get these pimples at the same spot with the same size that just keep coming back even if they get healed it’s like a never ending cycle it’s crazy.
      Me too i believe that drying out the skin screwed something and sebum is being produced to overcompensate because the zones that i have SD are the most oilest there question is : How can we fix the oilness cause i know for sure less sebum less SD the corelation is there and we know it.

      Reply
  33. Jay Profile Photo
    Jay

    Hey Joakim, Michael and anyone else interested – just posting my update on Nystatin (sadly it’s not positive as I was hoping).

    Tried it from last Monday (9th) until this Tuesday (17th) and didn’t see an improvement of any kind. Redness was still quite full on and if anything, it actually increased the amount of dry skin / flakiness I had around the nasal folds. It also had the strange effect of making the sebum on my nose almost ‘bead’ into little water droplets – like my skin couldn’t absorb it properly. Not sure on the reasoning behind that, but since ceasing application that hasn’t happened.

    Could’ve given it a bit more time, but the fact that I saw no improvement didn’t really give me much hope.

    There are a couple of older studies I’ve been reading up on that suggest Malassezia counts between healthy subjects and those with SD are very similar, and it’s in fact a sebum composition problem (which could also stem from internal issues or possibly genetics).

    I might go down the route of trying to increase LA in the skin whilst reducing oleic acid which seems to be an irritant and a primary cause in skin barrier disruption. Just need to save up and then I’ll try a mix of borage oil and possibly Michael’s topical Biom8.

    Reply
    • Hakan Profile Photo
      Hakan

      Hi Jay

      I never put any product on my nose or sides of my nose, since I don’t find the nose embarrassing compared to the fore head.

      This results in that I seldom have SD around my nose. But if I put on any Product the problems starts. However this method does not function on my fore head.

      Håkan

      Reply
    • Joakim Profile Photo
      Joakim

      Hey Jay,

      I’m really sorry to hear that. I had so high hopes for you — I’m really sorry if I got your hopes up too, now that it didn’t seem to work.

      You sound like a sensible guy, though, so I think you might be able to find another more holistic solution — sort of like the thing Michael has done. Also the approach you mention sound like a good start.

      I wish you all the best, and hope that you can be rid of the SD by other means!
      Best regards,
      Joakim

      Reply
      • Jay Profile Photo
        Jay

        Hey Joakim, was definitely worth a try – I think it might be better suited to those with active scabbing / scales which build up from SD, as I presume that is when SD has more fungal activity.

        I think my next course of action will be to try and repair the skin barrier. I can only assume that the redness and increased oil production on the nose area is a result of a severely depleted skin barrier which could have been caused by a variety of things over the years (or even genetics). It’s hard to tell whether SD is the cause or result of an impaired barrier! I’ll keep researching…

        A couple of things I’m interested in is diluted ACV topically, Michael’s BioM8 and possibly Green Tea in order to reduce sebum. But I’m sure I’ve had the red patches of SD prior to getting really oil, so maybe it’s not that at all? Might also consider oral anti-fungals just to see if it has any impact on the SD whatsoever, if it doesn’t, then I can deduct that the condition isn’t likely to be a fungal manifestation.

        Tough disease to manage, but keeping hope and trying out new things is all that we can do – aside from giving up that is – but that’s not really something worth considering when there are so many potential options out there. Would just be nice to have my life back instead of being a hermit and hiding away because of it!

        Thanks for the help Joakim, hope your skin is still doing well 🙂

        Jay.

        Reply
        • Joakim Profile Photo
          Joakim

          I actually just had a relapse, which I’m coming out of now. I stopped using nystatin for a while, because I hadn’t seen any symptoms in a while, and I wanted to stop stuffing my face with drugs if it wasn’t necessary. The SD came back a week ago or so, after a few weeks of cold turkey (mild symptoms compared to the full-blown outbreak I had last year). It might have been accelerated by cold, dry winter 🙂

          The point is: after using nystatin again for the last week or so the symptoms are down and everything is back to normal. So it still, luckily, works for me even after a year of more-or-less continued use. I don’t understand why it doesn’t work for you, but maybe there are different sub-strains or causes of SD, and ours differ.
          This time around my SD didn’t really evolve, or have enough time, to produce the scaliness. I mostly saw the redness coming back and knew what was up. So for me nystatin also clears the redness. I do not, however, recognize the beading of the sebum. I might feel a little more oily, but I don’t think that is a result of the nystatin, but rather a result of the compromised skin barrier. I’m only guessing, but the oiliness disappears with the other symptoms even if I continue the use of nystatin.

          But this little experiment goes to show that it comes back, if I stop using anti-fungals. I guess it shows that Malassezia is ubiquitous on most people if they don’t treat it. For some that’s no problem: maybe the immune systems deals with it, maybe it isn’t fed by the same sebum on “healthy” noses. But for some (us) it causes problems. I guess it would be better to treat the condition from the inside, changing the sebum composition through food and lifestyle, or empowering the immune system with vitamin D or whatever. Sometimes it’s as simple as sun and saltwater 🙂

          Keep us posted on your experiences, Jay. I don’t know if this is the best section of the website to update in, now that nystatin didn’t work for you, but I hope that you can still learn from and contribute to the community. And that you’ll get rid of it soon.

          Best wishes!
          Joakim

          Reply
          • Michael A. Profile Photo
            Michael A.

            Hi Joakim,

            Sorry to hear about the short relapse. Luckily the Nystatin was still effective though. And yeah your hypothesis is in-line with my research. There appear to be strains of malassezia which are able to adapt and become resistant to the Nystatin. Additionally, as Ian pointed out in one of his comments there are other micro-organisms which may be causing symptoms that closely resemble seborrheic dermatitis.

            In terms of the Malassezia, I strongly believe it effects some of us due to a combination of compromised barrier function, which is related to fatty acid metabolism and/or local fatty acid synthesis. Perhaps this is cause by another bacteria or something within our bodies that prevents optimal immune function. Overall though, topical still seem to play an important role as they allow us to live life while be figure out the underlying issue (which I still believe is important for long term).

            Have started work on a second edition of the book, hoping to go even deeper and really get to the core of the issue (and improve the structure of the last chapter).

            Happy holidays and best of luck in the New Year!
            All the best.

  34. Hakan Profile Photo
    Hakan

    Just ordered Nystatin cream from amazon.de.

    Restoraderm irritated my skin and made me scratch my face while sleeping. Raw honey made my skin very red and ACV does not seem to work any more. Tried it a few years ago and it worked. But not now.

    Biom8 does not irritade my skin but does not improve my flaking or redness. I have used it for five days now.

    My SD has been under Control the last years, but this moist long autumn in sweden made it much worse. I also had some coffe and liqueur. So I’m back on eating only healty foods and drinking water.

    I Think one big mistake which is easy to make, is to start eating and drinking unhealthy when the skin is gets good.

    Have started to take borage oil and flaxseed oil internally.

    Found a very intresting video where a doctor talks about the benefits of raw milk. Found it in a forum where someone treated rosacea and seb derm with raw milk internally and topically.
    http://www.rosaceagroup.org/The_Rosacea_Forum/showthread.php?25593-Raw-Milk

    Hakan

    Reply
    • Michael A. Profile Photo
      Michael A.

      Hi Hakan,

      Thanks for the update. Very unfortunate that the Biom8 didn’t produce the same results for you as it has for me.
      Are you currently using any other products/solutions? And how are you applying it? Do you massage it well into the skin?

      Hopefully the Nystatin provides some relief.

      Additionally, an oil free probiotic variation of the Biom8 should be available by tomorrow.
      It has broader anti-fungal activity and a skin repairing amino acid. Let me know if your interested of trying it out and I can email you a 100% discount code (only shipping). 🙂
      The only issue is that I haven’t really been able to test it as my skin has been clear from Biom8 usage..

      Best of luck mate.

      Reply
      • Hakan Profile Photo
        Hakan

        Michael, yes please send me a 100% discount code on the oil free product.

        I’m often thinking that maybe my skin is missing on good organisms to fight the bad ones.

        I used biom8 according to the instructions, but it seems as if my skin can’t stand oils at all.

        I read somewhere that one reason that sience has not fully solved SD is that there is several types of SD according to a studie. And most studies have not taken this into account. Will try to find this info again.

        I have used water based vitamin D topically over the last years. Maybe it was the healthy food that did it. Not sure.

        Have a great weekend

        Hakan

        Reply
        • Michael A. Profile Photo
          Michael A.

          Hi Hakan,

          Not sure if you had a chance to look through the eBook yet. The first chapter deals with the currently proposed reasons for seborrheic dermatitis in significant detail.
          The eBook is currently available for purchase on the site for $18.99 and here is the download page:

          Seborrheic Dermatitis the Owners Manual eBook – First Edition

          Not sure if I’ve set the price too high for just an eBook or perhaps I should even make it free. The only reason I had set it for sale is the research took an immense of time and any resources would help further develop the work.
          You opinion would be appreciated in this regard. Check your email for the eBook (will be sending to all other Biom8 users for free as well).

          Will update as the Probiotic version is available (planned to be released tomorrow).

          All the best.

          Reply
    • Michael A. Profile Photo
      Michael A.

      Hi Shane,

      Took a look. Strange how they don’t appear to have much information about the product listed (ingredients and etc).

      Not sure if you have seen it yet, but I’ve made my own all natural solution a couple months back. Which, came out of my research while trying to write a book on the subject.
      It’s called Biom8 and user feedback has been quite good so far. You can check it out here:
      http://www.biom8.com/product/biom8-conditioning-oil/

      Personally try to keep it’s advertisement on this website to a minimal, but it’s honestly been the best thing I’ve tried.
      My own write up on my experience is here.

      Hope that helps and look forward to any updates.

      Reply
      • Shane Profile Photo
        Shane

        Yeah I did notice that and obviously there will be many claiming to have the cure but in reality very few crack the code! But at the same time I like to keep an eye on new solutions or alternatives because maybe one of them will be the potion we are all searching for! Thats cool I wasnt aware that this was your product, Il check it out 😉 thanks, Shane.

        Reply
        • Michael A. Profile Photo
          Michael A.

          Hi Shane,

          For sure. Happy to hear about your results from the Nystatin as well. This would likely be something I try if Biom8 stops working, but hopefully it will never come to that. The only issue I somewhat have is my desire to stay away from commercial antifungals. Intuitively I feel somewhat uncomfortable with long term usage of them. Research shows that nytstatin is safe, it’s more of a personal preference. But at least out of the ones commonly used for seborrheic dermatitis, nytstatin is in part of natural origin. However, from my research there are various natural compounds that appear to show effectiveness which is on par with synthetics (what inspired the original Biom8 and the upcoming probiotic based formula).

          Hope things continue indefinitely.
          All the best and thanks for sharing your experience in detail.

          Reply
  35. Jay Profile Photo
    Jay

    Hey Joakim,

    Looks like the Nystatin cream has done wonders for you (and other people). Great find by your dermatologist and interesting that he recommended it over the ‘common’ antifungals, immunosuppressants and steroid creams.

    Keen to try this, but I’ve got my flakes / scaling under control and I’m simply looking to get rid of the very apparent redness from the sides of my nose and the red blotches on the bridge of my nose, did this help control your redness? I feel like Rudolph some days!

    What is the best place to buy this from for people in Europe outside of Germany / Denmark (particularly UK residents)? Bit worried about using my card on a website I barely understand, even with Google Translate, the lack of final confirmation on cost is a bit worrying for P&P etc.
    – Apons?
    – Amazon.de?

    Also interested in your take on SD and gut flora, I’ve been reading a lot about this. Especially the link between the gut and the rest of the body such as immune responses, diseases and how it appears inflammation seems to be the route of pretty much every modern day illness. Will also follow up with a comment about your SD clearing when you went abroad to the Philippines, this is something I’ve come across quite a lot in my research…

    For anyone else looking, the ingredients list seems to be the following for the Nystatin Lederle Cream:
    Nystatin 2.2%
    Cetyl stearyl alcohol (vegetable)
    Water, purified
    Sodium hydroxide
    Isopropyl myristate
    Polyoxyethylene (20) monostearate
    Sorbic acid
    Glycerol 85%
    Lactic acid

    The only worrying ingredient is “Isopropyl Myristate” which is an irritant and quite bad for anyone who is prone to acne. Might be worth watching out for as this could cause issues. Lactic acid is also an AHA.

    Reply
    • Joakim Profile Photo
      Joakim

      Hi Jay,

      yeah, I’m pretty happy with my find as well. I admire Michaels tenacity — that he keeps looking for a completely natural, drug-free solution — but this has just so simple and effective for me that I don’t think about it too much anymore. I don’t know, now that winter is coming I might have to use a bit more of the Nystatin — maybe on a daily basis — but during the summer at least, I don’t feel that I lather my face with drugs. There will be days and even weeks without use. So I think it’s at an acceptable level.
      Maybe winter will change that, but if I started having problems again I would stop the coffee and alcohol for starters and look into my diet to try and mellow the inflammation. Right now I don’t have to watch out for anything in particular — not that I’m aware of at least. I did start eating vitamin D again ever since daylights saving time, but that is good for so many things in these dark months 🙂

      So yes, I did manage to control the flaking AND the redness with nystatin. It’s been almost a year since I had that Rudolph feeling that you mention. It’s so great to not be self-conscious about your physical appearance all the time. So I recommend giving it a shot, but otherwise look into Michaels great research on the topic if nystatin fails to help you — but after seeing a few success stories by now I’m sorta almost confident that it will work for you too. No promises, though! 😉

      Vero commented a long time ago, saying that she ordered it from Germany to the UK via http://www.parcemed.de/, but recently she gave an update, and I think she ultimately just used amazon.de — specifically: http://www.amazon.de/gp/switch-language/product/B00B5CO85A/ref=cs_switchlang?ie=UTF8&language=en_GB

      I am still quite sure that the whole thing is connected. Both indirectly through the interactions between you and your bacterial gut flora, but also directly on your skin as is the case with sun and salt water in the Philippines. There are so many factors to account for.
      But I think what has really helped with the nystatin treatment is that for once I have been able to completely kill the fungus, thereby helping my skin establish a normal, commensal flora of benign bacteria that occupy the sites where the fungus would live. So now it takes more stress and upset to throw my skin off-balance, so to speak. That’s my thoughts at least, and I’m sure there is some truth to it, but it might not be the only thing at play. It is a complex matter for sure…

      Finally, thank you for posting the English ingredients list. Informed choices are the best ones, so thank you for facilitating that.

      I hope you can trust in the german amazon and will end up trying and succeeding with nystatin.
      Stay in touch, both if you have more questions or experiences to discuss, or if you just end up checking to say “it’s gone” 🙂

      All the best, Joakim

      Reply
      • Jay Profile Photo
        Jay

        Hi Joakim, thanks for your reply!

        Excited to hear that it cleared both aspects of your seb derm remarkably quickly, I’m hoping it will have the same effect for me. I ordered it from Apons last week (Monday), and as soon as I started typing this, the postman showed up with a German delivery – so it takes roughly 7 days and costs about £13.50 at the current exchange rate including delivery.

        Couple of quick questions regarding the application of the Nystatin:
        – Did you wash your face before applying the cream?
        – How many times a day did you apply it and when?
        – How much did you use per application? (Pea sized ball or less?)

        Completely agree with your point that it seems to be multi-factor issue that could involve the gut and skin flora. Very interesting that a different environment (Philippines) with sun and possibly different water would help so much; I’ve seen people say that travelling to Thailand cured their Rosacea and various other skin issues. If you weren’t paying attention to diet so much and consuming alcohol, that would suggest that the gut may not play a huge role in the development of your SD. Could the UV light be enough to put the bacteria / fungus on the skin into remission? Could it simply be the water not aggravating the condition and giving your skin time to recover and repopulate with commensal bacteria?

        The fact that SD comes back upon returning to normal environments or stopping treatment with creams would suggest that the bacteria or fungi almost become ‘dormant’, and re-activate when the conditions suit them. So it might not be so much that they’re being killed, but that they’re being made inactive? I think Michael linked a video of skin microbiota and dormancy in another post – was extremely interesting and insightful (found it: https://youtu.be/nb98ZLluAGw)

        Will start application of the Nystatin either tonight or tomorrow and give feedback on how things progress for better or worse… hopefully better though 🙂

        Reply
        • Joakim Profile Photo
          Joakim

          Exciting news! 🙂 I’m looking forward to hearing how it goes!

          I usually apply the creme after a shower, which I usually do in the morning. But as I mentioned, I don’t really have any fanatic schedule or routine. Some days, I wont use it at all, and sometimes I will feel a SD-sort of sensation on my skin or notice small signs of irritation or redness and just apply some before bedtime to be proactive – maybe even without a face-wash. One thing I try to do, though, is to complete at least 4 days of treatment if I feel the need, in order to combat resistance. It’s just something that I do, not something I was told to do, but I reason that small doses once in a while might select for the more resistant fungi. Sort of like with other antibiotics, where you have to complete a full treatment, even after the symptoms disappear. But you don’t have to worry about that at first, as you should use it daily for at least 2 weeks, I’d say. By then, if it’s effective for you, I hope that you are almost back to your normal self 🙂

          Initially, I might even have used it twice daily. I actually cannot recall. But I do remember my dermatologist saying that you don’t really have to be worried about using “too much” – not like with hydrocortisone. So you can do that, if you feel like it – morning and evening. That doesn’t mean, however, that I applied a face mask of nystatin to my face every night. Just work it into the skin wherever there’s inflammation. I use less than a pea now, but maybe a pea-sized ball is alright in the beginning. You’ll figure it out. But work it in gently, don’t leave a layer on the skin. And then you’ll diminish your consumption down the road. I’m only on my second tube after using it on-and-off for a year now.

          I have not had a full-blown flare-up since forever, so I can’t actually tell if it would comeback if I completely discontinued the use of nystatin. The reason I still use it from time to time is just to be proactive and because I already have it. I’ve been very casual with the use during summer without problems. Last spring, however, I had a flare-up, but maybe it wont happen again? Maybe my hormone levels have changed — and with that the composition of my nose-lipids –, maybe I’m not as stressed anymore, maybe by using nystatin I have helped my body reestablish a natural balance that it can now maintain after this initial, helpful push. I will find out, I guess, when I finish this tube. I might go cold-turkey for a while then, and only buy a new one if it returns.

          The trip to the Philippines is an example of the horrible self-diagnosis one can perform when dealing with SD. The effect was non-negotiable: The SD disappeared. But I changed SO MANY things. I was living in Beijing at the time, studying, and went on vacation to the Philippines. So my diet changed from Chinese food to Filipino food, my environment changed (sea water, more direct sun-light, less pollution, being outside much more, etc.), I went from stressful work to relaxing holiday and so many other factors. There’s no real conclusion to be drawn from the trip except that something — one or more of those changes — had actually made the SD go into remission. That’s the one thing I gained from that: That it was possible to treat. And that gave me hope and motivation to keep looking for a solution.

          End of speculations for now — work’s a-calling 🙂

          But good luck with the treatment! I wish you all the best.
          Imagine: in a week or two, it might be all gone 😉 Just in time for Christmas!

          Reply
    • shane Profile Photo
      shane

      Hey, I purchased from Apons in Germany. I was a bit apprensive ordering from websites I know nothing about and especially that most of the correspondense is in German. But it arrived last week so it seems to be fine. Surely there other products available even on perscription that match the ingredients in Nystatin. Im on my 3rd day using the cream and its doing a lot of good already!!

      Reply
      • Met Profile Photo
        Met

        Shane please let us know if u have any success with it as well, here in italy i couldnt find a nystatin cream with no corticosteroids included so i would have to order it from amazon.de but i want to be sure before applying new stuff on my face. I ve been suffering this condition since i was 19 y old. It worsened along the years. First was only on the nose sides. Then on the hairline and in the end all over the scalp and the forehead. I keep it at bay using aluseb (not sure if this product is sold outside italy too) wich cleared it completely on the hairline but couldnt do much for the forehead. Recently the situation on my scalp got worse and i cant seem to find a shampoo that doesnt irritate it. Showering it s a nightmare. Well anyway just let me know about your results with nystatin and possibly this new product sold in uk. Last thing: sunbaths and the salty water of adriatic sea always clear it completely for me during summer. But it always comes back..

        Reply
        • Joakim Profile Photo
          Joakim

          I’m sorry to hear about your struggle, Met!

          I will say, though, that there is hope: I’ve said it before, but after I started using nystatin on my face alone, the inflammation disappeared everywhere, including on my scalp and chest!
          I have no idea how it is all interconnected, but there is a chance that you will see the same effect.

          Fingers crossed!

          Reply
        • Shane Profile Photo
          Shane

          Hi Met, Yeah I share your struggle and like you it appeared either side of my nose, spreading outwards as time passed. Forehead and on my chin etc. So let me say I have tried several creams and nothing has ever ever worked! I have tried Apple Cider Vinegar and that hasnt work. Nystatin is a life saver!!! This is only my 5th day using it and my skin has completely cleared up like never before. I apply it twice a day Morning and Evening. My skin hasnt lookined this good in maybe two years or more. I bought it from Apons (German company) took about a week to arrive. Anyway just take my word, this cream is the thign Ive ever tried. Shane.

          Reply
      • Jay Profile Photo
        Jay

        Hey Shane, glad to hear your Nystatin treatment is going so well, amazing news! Just got mine delivered today, so will be trying it out very shortly.

        I noticed you apply it twice a day in the morning and evening, do you wash your face or anything with water first? And roughly how much do you apply? I want to put enough on to be effective, but not too much that it suffocates the skin (plus the tube costs a fair bit, want it to last, especially if it works!)

        Thanks,
        Jay

        Reply
        • Shane Profile Photo
          Shane

          Thats good Im glad you ordered it. I havent estalbished any kind of routine around it yet. I mean the first time I used it was just directly in the evening time no pre wash. But mostly I apply in the morning then later in the evening perhaps after a shower. I did use a generous amount for the first few days. I wanted to really kill the bacteria. I noticed after maybe 4-5 when I wiped hard after the shower like a film just came away. It was like fresh skin underneath. So so so soft, no roughness, it was like for the first time in 3 years Id seen my skin like this. So now I use a little less but still going twice a day. My forehead has completely cleared up. Either side of my nose is about 90% vanished, no soreness itching or redness, its just like I can still see the scarring of it?? Im hoping that goes too. Let me know how you get on!

          Reply
    • Joakim Profile Photo
      Joakim

      Hi Jay,

      I wrote you a long reply this morning, but I don’t see it yet. I really hope I didn’t mess up. There was some good stuff in there! 😀 Hopefully it’s still just awaiting moderation, but it has never taken this long, so I’m losing faith.

      I’ll get back to your questions soon if it doesn’t show up. But right now, I’m going to bed!

      Best regards,
      Joakim

      Reply
      • Joakim Profile Photo
        Joakim

        Okay -.- I see it now. It popped up when I submitted the other one! Uhm… yeah, I think it’ll be all right.

        Sorry for the impatience, Michael! 🙂

        Reply
        • Michael A. Profile Photo
          Michael A.

          No problem 🙂
          Not sure why your comments don’t bypass the moderation cue. Usually, repeat commentators don’t go into moderation.

          All the best.

          Reply
  36. Hakan Profile Photo
    Hakan

    Thanks for an amazing site and your helpfull way of living.

    I have ordered biom8 and I’m also looking forward to the probiotic spray when it’s ready for sale.

    I just bought Restoraderm as it’s available in Sweden. I will use it until the biom8 arrives.

    There is a group on yahoo that clears sed derm with a strict food protocol. It mainly consists of vegetables and fruits and processed foods are not allowed like sugar, fries, bread, high fat food, meat and so on.

    I made an incorrect post the other day saying that the Nystatin from amazon i Germany contains aluminium hydroxide. However the cream Nystain USP does contain aluminium hydroxide.

    I have not seen the list of ingredients of the Nystatin cream from Germany. Does any one have this product called Nystatin Läderle? Does it contain aluminium?

    The reason I’m concerned for this is the many scientific based papers that states that aluminium can cause seriouse diseases like cancer. Search for aluminium on mercola.com.

    Thanks for your time

    Hakan in Sweden

    Reply
    • Joakim Profile Photo
      Joakim

      Hi Hakan,

      I don’t think I can post a picture here, otherwise I’d just show you the box, but as far as I can tell, there is NO aluminum in Nystatin Lederle Creme. Not unless it is disguised as something else 🙂 it goes:

      1 g Creme enthält ALS Wirkstoff:
      100 000 I.E. Nystatin entsprechend 22,73 mg
      Trockensubstanz (Ph. Eur.)

      Sonstige Bestandteile:
      Macrogolstearat 1000, Cetylstearylalkohol, Isopropylmyristat, Glycerol 85%, Sorbinsäure (E200), Milchsäure (E270), Natriumhydroxid, geneinigtes Wasser.

      That’s the genuine German version. When I initially started using the creme, I looked up the ingredients, and I don’t recall any of it containing aluminum. But now you can look for yourself 🙂

      Best of luck!

      Reply
    • Michael A. Profile Photo
      Michael A.

      Hi Hakan,

      Thanks for the feedback.

      Hope that the Biom8 works out for you as it has for me.Will make sure to update you once the probiotic spray is ready. Haven’t had much opportunity to test it as my skin has been clear since starting the Biom8.

      My diet has shifted quite a bit, but I do eat quite a bit of bread, specific desserts, and don’t stress too much when eating out. The biggest changes for me have been reduction in vegetable oils and vegetable oil containing foods (particullarly deep fried). And the second thing is a reduction in the amount of red meat I ate. Mostly stick to seafood and moderate amounts of poultry.

      Thanks for the clarification on the Nystatin. Haven’t personally used any Nystatin products. I’m sure that you can get a custom formulation from a pharmacologist. Nystatin is used quite broadly for many fungal related issues.

      Have you had a chance to read any of the draft book chapters?

      All the best Hakan.

      Reply
      • Hakan Profile Photo
        Hakan

        Michael I will read your chapters this weekend.

        My seb derm dissapeared from legs, arms, cheast and thighs when quiting processed foods, candy, desserts and gluten. Final battle is the face.

        Scalp is good. I’m using an all natural schampo from a danish comany Urte kram. I pull my fungers hard on the scalp and drag away any signs of dandruff when showering. I don’t use anti-dandruff shampos.

        Made a post under your regimen 2.0 regarding flaxseed oil, borage oil and fish oil taken internally. Very intresting post from curezone. Thanks Joakim for the nystatin ingredients.

        Have a great weekend all,
        Hakan

        Reply
  37. Hakan Profile Photo
    Hakan

    Joakim, thanks for the info on Nystatin cream. Whats the product name of the cream? What does it contain?

    The Nystatin cream from amazon in Germany contains aluminum hydroxide which is a big issue. The side effects from aluminium in humans are very serious. Read more about aluminium on mercola.com.

    Me facial SD is bad at the moment but I will not use aluminium products. At home we use deodorants and salts for cooking that are free from aluminium.

    Best regards

    Hakan from Sweden

    Reply
  38. Shane Profile Photo
    Shane

    Hi Guys,

    I purchased Nystatin cream from Apons in Germany and it arrived today here today in Ireland. So I’m just checking in today to say I’m really hopeful and desperate it will work. I will keep you all up to date about how it works for me and hope to God I have positive results. I haven’t made any dietary changes or any other preventative measures so let’s see does this cream have an effect! Shane.

    Reply
  39. Harry Profile Photo
    Harry

    I had a similar experience with Nystatin though in a powder form. Basically I was at my Podiatrist for athletes foot and she prescribed with A nystatin talc powder which she told me was an Anti-fungal. Needless to say it worked very well for my athletes foot, but then I got an idea. After reading that anti-fungals were the way to go in treating seb-derm which I had been suffering with for a long time. That coupled with the fact that I felt creams in general made my face worse, I decided to try putting the foot powder on my face. I would put a little on the affected areas every night before bed and after only a few days I could see drastic results. In my opinion this has been my best treatment method so far and would highly recommend it to anyone struggling with seb-derm.

    Reply
    • Joakim Profile Photo
      Joakim

      Thank you, Harry. It’s great that more people are adding to the story and compiling some sort of proof that nystatin might be a viable treatment. At least for some of us 🙂 I’m happy to hear that you got rid of it!

      Reply
  40. Vero Profile Photo
    Vero

    Hi, this is a response to Eunice who was interested in ordering Nystatin Lederle Creme for US delivery. This is prescription free in Germany and there is a German pharamacy that sells this product on Amazon.de (German Amazon) and will ship it to the USA.
    Here is the link – you may need Google translate to read the page but I hope this helps.
    http://www.amazon.de/NYSTATIN-LEDERLE-50g-Creme-PZN/dp/B00B5CO85A

    Reply
  41. Eunice Profile Photo
    Eunice

    Hi Joakim and Michael I’m trying to order the Nyastin, but I want to know the best site to order it. Or if it’s safe to order it. I live in the US. I would really appreciate if you would tell me where I can get it from or if someone has ordered it before from the US.

    Reply
    • Michael A. Profile Photo
      Michael A.

      Hi Eunice,

      Haven’t had experience with order Nystatin in the states. However, I think the easiest would be to try and get a prescription.
      It’s used widely in a lot’s of different pharmacy preparations. Here in Canada clinic visits are covered by public health plans.

      Hope that helps.

      Reply
  42. Kay Profile Photo
    Kay

    Hi Joakim,

    That’s so great that you were able to find something that works for you! I recently got Nystatin so hopefully I see results. I have only been using it for a day, but I was wondering, when you started using it, did it seem like the scaly, oily parts were kind of “shedding”? Like the overgrowth of yeast was sort of coming off? I guess I just want to know what signs to look out for to determine if it’s working. Thanks again!!

    Reply
    • Joakim Profile Photo
      Joakim

      Hey Kay,

      yeah, initially I had that sort of peeling experience. I think it’s just excess skin or something, I’m not sure that that is the yeast 🙂 Anyway, in my experience, that’s normal in the beginning. Hopefully your skin will heal up within the first week or so and come back to normal.

      Please share your experience 🙂

      Best regards, Joakim

      Reply
  43. Vero Profile Photo
    Vero

    Hi Joakim and Michael
    A few months ago, I commented on Nystatin and how it has helped me with SD on my face.
    I noticed that my particular SD flares up with a tingling sensation or prickling sensation on my face as though the nerves were talking through the skin – exertion, physical, mental – mostly positive and also good stress bring it out too. Gardening brings it out on my forearms – I will try Nystatin there.
    There seems to be a link to digestion, as was discussed on this forum before. The metabolism seems to speed up a bit. I wonder is there is a link to thyroid overstimulation.
    Strangely, for me at least, a few spots of Nystatin applied on the SD parts of the face seems to have a positive effect for the rest of the skin on the face – i.e. almost no need for moisturizer now.
    Again, thanks for the Nystatin tip and for sharing this and other useful experiences through this forum.

    Reply
    • Joakim Profile Photo
      Joakim

      Hi Vero,

      it’s good to hear from you again. It makes me very happy that you’re still in control of the SD. It’s nice to know that my post has made some difference 🙂

      I have a personal feeling — I’ve not done the thorough research, though — that it could be linked to our immune system and bacterial flora, which in turn are also greatly influenced by our gut and digestion, like you mention. As far is I know, it the yeast Malassezia that’s the cause of SD, and it’s present on most people. It’s causes opportunistic infections. I actually considered inoculating my face with bacteria that are a natural part of the colonization on our skin. This would leave less “room” and nutrients for the malassezia fungus to settle in and grow.

      I don’t know if your research has carried you this way, Michael, but I’ll suggest it anyway. I was looking into the Corynebacterium that inhabit the skin, and in particular the Corynebacterium lipophilicus that likes the sebum that the Malassezia yeast also seems to thrive on. The idea is then to have this harmless bacterium living on my nose instead of the yeast that causes all this trouble.

      These bacteria are usually introduced in early stages of life, and if something goes wrong, then other, more harmful guests may take their place. I guess that’s why SD is also seen a lot in young children that have yet to develop the full, balanced community of bacteria. Also, with a lot of people living more and more sterile lives, we might not have been introduced to these bacteria, or at least not to the same extent. If you are born by C-section and given formula as a baby then you don’t develop the same micro-flora and immune system. This is related to all sorts of allergies and problems.

      I think I’m predisposed to other types of fungal infections as well — not just SD — which might be linked to a “hole” in the micro-flora of my skin that should be taken up by harmless bacteria instead of the fungi. If I recall correctly, I was born by C-section, which might have robbed me if some if the good stuff you get exposed to (in a microbiological sense) by a natural birth.

      I’m not sure of the mechanics, but the SD kicked in when I was about 20 and waving goodbye to my teenage years, and maybe some hormones or whatnot — hormones are not my field — which could have kept the balance in check somehow. This is quite speculative, but it’s an educated guess if nothing else 🙂

      I sort of went off on a tangent here, but maybe this will get your head-gears spinning, Michael 🙂 Maybe someone will come up with a sort of permanent “bacterial vaccine” or some other clever ploy in the future that can fix the issue for good.

      Either way, I’m happy that we can just kill the yeast with nystatin in the meantime. But like you, Vero, I’d like to keep the amount of administered medication to a minimum, so treating the problem at its core would be a great improvement over the symptomatic treatment we are using now.

      Reply
  44. Debbie Profile Photo
    Debbie

    I have been itching for months and couldn’t find anything to help. I read your article and added the nystantin to my daily routine, and guess what I am finally not itching. I see my dermatologist next week, so excited to tell her what I found

    Reply
    • Michael A. Profile Photo
      Michael A.

      Hi Debbie,

      Great to hear it worked so well.
      All thanks to Joakim for submitting this solution.

      Best of luck.
      If you have the time, let me know what the derm says.

      Reply
    • Joakim Profile Photo
      Joakim

      Hi Debbie,

      It makes me so happy to see that people still stumble upon this and find it helpful 🙂

      Now I don’t know if you’ve seen the dermatologist before, but the appointments sounds like a good idea. Nystatin is essentially just an anti-fungal, so it doesn’t work against SD exclusively. The reason I mention this is because you only described the itching, and to me there were so many other symptoms, so from that alone it could also be something else. Maybe you already have a diagnosis, but if you don’t then the doctors appointment is a really good idea 😉 and like Michael, I’d love to hear the dermatologist’s response..

      I’ve been able to cut my routine down to only using nystatin. From the responses I’ve read in here people have had different degrees of success, and some still have to watch out for certain foods or follow their old cleanse and moisturize routines. But you can experiment with that yourself 🙂

      I was also worried that I would build up some sort of tolerance or the SD would become resistant to the drug, but so far it’s still working for me without any ill effects. Actually, for the last month or so I haven’t used it at all, because of all the sun I’m getting during summer. Now, slowly, I can feel it coming back – it’s still pretty much unnoticeable, but I can feel the skin around my nose is less elastic. But after using it for a few days I’ve been able to put it back in check! That’s what I’m most excited about: that I’m finally in control of my face.

      Hopefully, you will have a similar experience.
      All the best, and good luck at the dermatologist.
      Joakim

      Reply
  45. chicken Profile Photo
    chicken

    Hello,

    This question is more geared toward Joakim. I was wondering, would you mind posting your exact regimen with Nyastin, both when you started out and how much you use it now? Did you use it once a day on your face every night for those two weeks? Did you wash your face before applying it? Did you wash your face in the morning during these two weeks too? How often do you use it now? Do you wash your face still with a cleanser and moisturize since its cleared, or what is your regimen look like now? Basically, id just really love to know your entire regimen, both during the clearance of your SD and since then. Thank you for your time.

    Best,

    Reply
    • Joakim Profile Photo
      Joakim

      Hello 🙂

      So, initially, I started using the nystatin last December. If I recall correctly, most of the symptoms were gone after one week. After two weeks it was completely gone, I’m sure. I’ve continued using it ever since, but I’m not that thorough anymore. Initially, I used it every day, but now that I’ve knocked it out, it seems that I don’t have to use it daily. I got careless during the winter, and I had a flare-up, because I didn’t use it frequently enough. The flare-up was probably also coupled with a stressful time in my life 🙂 So I don’t consider myself completely cured, and I still use nystatin to this day. Now that it’s summer, I don’t use it very often. Just whenever I remember, so maybe a few times a week (2, 3, or 4 times). I’m quite sure that the sunlight helps.

      I actually use it in the morning, usually after I shower. And that’s pretty much it. I don’t worry about washing my face in the evening before bed, or use any moisturizers or cleansers. I used to moisturize since I thought it could help my dry skin, but I think the dry skin was a symptom of the SD, so now that it has gone, I don’t feel the need.

      Other than that I use a shampoo containing zinc pyrithione and climbazole and a conditioner for normal hair, when I shower. Again, for me, it doesn’t seem like I have to be have careful with the planning. I don’t wash my hair daily, I only do it a few times a week, whenever I feel like it, but I never use any other products than those two. Unfortunately, it’s not an international brand, but I’m sure you can find identical products.

      Now that it’s summer, I haven’t found any problems using sunscreen in my face. I was a little bit worried that it might be a food-source for the yeast, but so far I haven’t had any problems. Also because I normally only apply sunscreen when I go into the sun, and as I wrote above, I find that the sun helps keep the SD down. So I guess if the sunscreen was in any way a bad thing, it’s counteracted by the intense sun.

      I hope that covered the details. If there’s anything that I failed to explain, or something I missed, feel free to comment again and specify 🙂

      Reply
  46. Renita Dominique Profile Photo
    Renita Dominique

    My son has SD (head, face, chest and back). The creams prescribed by the dermatologist (Ketoconazole creams and shampoo, other steroids creams and oral antibiotics) worked okay based on how well and how often they were used. His flare-ups would be severe to the point of getting an abscess or two in his face requiring the oral medicine.

    My grandson’s pediatrician prescribed Nystatin cream and ointment for a diaper rash. I was extremely impressed with how fast and how well it worked. I researched other uses for the Nystatin and was pleased to learn it can be used for SD. Good results were noticeable overnight. Although the ointment is easier to apply to face and scalp, the cream does well on chest and back.

    Thank you, Michael, for confirming.

    Reply
    • Michael A. Profile Photo
      Michael A.

      Hi Renita,

      Thanks for checking in. Glad to here the Nystatin working. It’s strange how common Nystatin is.
      A short while after Joakim pointed it out through the website, I actually found a tube laying around my house (someone must have given it to me).

      Hope everything resolves itself. It’s difficult when younger children go through this as they seem to get hit by it quite hard. Also, since they are still kids it can be hard to find a suitable approach.

      It would be interesting to hear how things turn out.
      Wish you all the best.

      Reply
    • Joakim Profile Photo
      Joakim

      It is actually not that surprising, and not the first time I hear a story like that. Nystatin is by no means an unknown, obscure drug. It is on WHO’s list of most essential medicines, so I guess it’s pretty widely used to treat a number of yeast infections. But maybe the idea of using it to treat SD is relatively new, or at least unconventional. The go-to methods seems to be the hydro-cortisone cream and ketoconazole shampoo – which didn’t really work for me 🙂

      But I am happy to hear that you are seeing progress.
      All the best to you and your family 🙂

      Reply
  47. Barbara Profile Photo
    Barbara

    Finally! I’ve been dealing with SD for over ten years. I hate it. It’s all over my scalp and behind one ear. Occasionally, I’ve had to use an antibiotic for some reason or other over the years and loved that my SD went away for those precious ten days of using the drug. But the SD always came back.

    When I was doing chemo a couple years ago my SD was totally gone for all those months! Hated the chemo – but loved the freedom of a scaly scalp! I’ve just been given Nystatin for yeast under the breast. It didn’t work, but I’m going to use it on my head to see what happens. The antibiotic I’m on is helping under the breast. Go figure.

    I have rosacea. Does this all intermix in some way? Yeast? Oily skin? Rosacea?

    Reply
    • Michael A. Profile Photo
      Michael A.

      Hi Barabara,

      Sorry to hear that you’ve been battling it for so long.
      Yeah, they all seem to be interconnected. However, just yesterday I read that oily skin isn’t really correlated with SD (source).

      Here’s something interesting I learnt earlier this week. An infants skin turns over about every two weeks (old skin sloughs off, new skin takes its place). As we get older this process slows down and increases to about 2 months. However, in inflammatory skin disorders like psoriasis and seborrheic dermatitis the whole skin eco-system turnover can be as short as only a single week. (Here‘s the video)

      This kind of lead me to thinking that perhaps a steroid cream provides that extra kick required to allow the skin cells to mature more rapidly yet still healthy. If the cell turnover is still super short and the steroid cream is stopped they go back to not being able to properly mature. Now without properly developing, the skin cells become much more susceptible to invasion by foreign bacteria.

      It’s just a theory, but currently looking into it.

      All the best. Look forward to any updates.

      Reply
    • Kathryn Profile Photo
      Kathryn

      I developed SD on my face two years ago at age 61. After four dermatologist I have learned I have both slight Rosacea and SD. It started on my eyelids horrible flaky red skin they called Blephartis. I had to stop wearing my contacts. Then it briegly moved to forehead and disappeated moving to side of nose, eyelids & later around my mouth area. I have read about 30% have both and the effect each other.

      I have had SD, eczemea conditions all my life with long periods of normal skin but never the face. It was confirmed my extreme stress, moving to a very hot area were the main culprits. I also have had it under my arm pits and breasts for twenty years. I have learned it is genetic, no real cure. But, I will certainly try this Nystatin cream.

      Reply
  48. Kelly Profile Photo
    Kelly

    Thanks for the information. I guess I’m lucky that it is only seen by me and I have very long, thick hair. I just hate feeling so gunked up. I am trying the Nioxin treatment right now, I shall see how this turns out. I’m keeping the nyastatin at the back of my mind though.

    Reply
    • Michael A. Profile Photo
      Michael A.

      Hi Kelly,

      Yeah, it’s an unpleasant feeling for sure.
      First time I’ve heard about the Nioxin.
      Let me know how it goes.

      Best of luck.

      Reply
  49. Kelly Profile Photo
    Kelly

    I feel like I have had SD for many years but ever since I had my first child it has only gotten worse. I was diagnosed by my doctor and I’ve tried the Nizoral shampoo, t-SAL, T-Gel. I’ve also tried no-poo, baking soda and ACV with limited results. I just hate having this gunk on my scalp. It’s the only location I have SD. I also have thick long hair which makes it difficult getting to the scalp to treat it. I am intrigued by this nystatin and I have also heard by controlling the yeast growth internally helps as well. Thanks for having this site! I know I’m not the only one, but it’s not something that is talked about often.

    Reply
    • Joakim Profile Photo
      Joakim

      Hi Kelly,

      as I’ve mentioned a few times before, I have never applied nystatin to my scalp. I only use it on my face. However, for some reason, it was only when I started using nystatin on my face that I was able to control the dandruff and scaling on my scalp. I don’t know how it works if you only have symptoms on your scalp, and if you can apply it there. A few people above have tried using it on their scalp, but I’m not sure about the results. Give it a try if you haven’t had any luck with other treatments. I haven’t had any adverse effects, so I guess it wouldn’t hurt to try.

      Best of luck,
      Joakim

      Reply
    • Michael A. Profile Photo
      Michael A.

      Hi Kelly,

      Same as Joakim. Once I controlled the SD on my face it cleared on my scalp. However, I found relief using non anti-fungal methods. Part internal and part simple cleanser/wash. Over the past few weeks I’ve been diving deep into medical research into SD. Hopefully sometime soon I can have a post with deep analysis of what SD really is, or at-least my analysis of what modern day research has to offer.

      Here the gist of what I have so far. Most of the dermatologists believe it is due to fungus/yeast. Most modern day has research has been trying to find a clear cause-relation, but so far everything has been inconclusive. However, anti-fungals typically have good results by simply removing all bacterial activity on the skin (healthy individuals have no issues to this activity) and thus, the approach typically taken is anti-fungal medication. However, after looking at a wide variety of related inflammatory skin conditions (eczema, psoriasis, rosacea), it seems that there is a close relation to issues of the immune system here and hormonal dis-balances.

      Even though I’ve been free of SD for about a year now, I still have a strong urge to really find what happened to my system. Would hate for this thing to come back later in my life.

      Sorry for going off a bit (relative to your comment). Lol. Was just pounding through research papers all day and you’re the first comment on my todo list. 🙂

      All the best.

      Reply
  50. val Profile Photo
    val

    I’m an RN and have used nystatin successfully on myself and my elderly patients for facial SD. It’s not a cure, but the symptoms are quelled with regular use. I have also had good sucess using a dog shampoo called Oxiderm PS for my scalp SD which I have been continually plagued with since childhood. After using it a few times per week for a few weeks I was free of all the itching redness and scaly dander for over 6 months. I had high hopes that I was cured but now it’s back again and I need another bottle. I found it works better than Nizoral for sure. I’m thinking of experimenting with mixing in nystatin into a shampoo and letting it set on my scalp for a bit before rinsing.

    Reply
    • Michael A. Profile Photo
      Michael A.

      Hi Val,

      Thanks for checking in. Really interesting to see a person from the medical field on here. 🙂
      Yeah, my scalp SD has been present since about the early teenage years. This was easy to control though, simply by using H&S regularly. However, when it spread to me face things became much harder to control.

      If you have the time, it would be interesting to hear your opinion on the approach that worked for me (outlined here and at the last two sections here). Since I started the approach outlined, I haven’t needed to use any anti-fungal shampoos for me scalp even. Not sure why (either lucky with shampoo choice or the l-glutamine did something..). Hope you have the time to look this over and provide some input.

      Additionally, I’ve randomly came upon this wash a while back. Have never tried it for my SD, but I ran across it in some medical literature. You seemed like the perfect person to run this by, as it is supposedly used frequently in medical settings. I would imagine the iodine would be quite effective for controlling the bacteria responsible for SD.

      All the best.

      Reply
    • Michael A. Profile Photo
      Michael A.

      Hi Val,

      Thanks for checking in. Really interesting to see a person from the medical field on here. 🙂
      Yeah, my scalp SD has been present since about the early teenage years. This was easy to control though, simply by using H&S regularly. However, when it spread to me face things became much harder to control.

      If you have the time, it would be interesting to hear your opinion on the approach that worked for me (outlined here and at the last two sections here). Since I started the approach outlined, I haven’t needed to use any anti-fungal shampoos for me scalp even. Not sure why (either lucky with shampoo choice or the l-glutamine did something..). Hope you have the time to look this over and provide some input.

      Additionally, I’ve randomly came upon this wash a while back. Have never tried it for my SD, but I ran across it in some medical literature. You seemed like the perfect person to run this by, as it is supposedly used frequently in medical settings. I would imagine the iodine would be quite effective for controlling the bacteria responsible for SD.

      All the best.

      Reply
  51. Valerie Profile Photo
    Valerie

    Read a lot here, nice to find you all. I think the answer is out there but the dermatologists won’t tell us. I bet we find it though. I tried the listerene protocol last year and killed my scalp sd for months…but fall came and so did sd…and I can’ t get a handle on it again. ( I put listerene on scalp, put shower cap on and left it several hours). As a female I have lots of hair these protocols screw up trying to get at my scalp. Do NOT trust presc. Strength Nizoral…it fried my hair texture (actual side effect). Any Nystatin for scalp treatment…oral?

    Reply
    • Michael A. Profile Photo
      Michael A.

      Hi Valerie,

      Thanks for checking in. Strange enough I’ve never actually tried the listerine myself. However, I have heard of others using it.
      Definetly agree with you on the Nizoral. That stuff is intense. After just one single use I knew that it was overkill. It felt like I just nuked my skin and killed every single living organism on the surface. Hair felt like dry hay.

      Is your seborrheic dermatitis strictly limited to the scalp?

      Thanks again for checking in.

      Reply
    • Joakim Profile Photo
      Joakim

      Hi Valerie,

      I’m not sure that the is a nystatin treatment specifically for the scalp. One guy on reddit, however, told me he had used the creme in his ears and on his scalp, where he could apply it. I think he had good results. So I guess you can just apply it where-ever is accessible.

      I don’t know about the oral treatment. I think it is different at least. I wouldn’t be allowed to donate blood if I used the oral treatment at least. But it’s outside my knowledge, so I can only guess. I recommend talking to a professional 🙂

      For me, I never had to use it on my scalp. I applied it to my face, and somehow that made the stuff on my scalp and on my chest disappear as well. I only use a shampoo containing zinc pyrithione and climbazole and a conditioner also for sensitive hair and scalp.

      All the best.

      Reply
  52. Francis Underwood Profile Photo
    Francis Underwood

    Hi Joakim,

    Thanks for the detail. I used Ketaconozole for a while but I guess my skin got used to it becuase I had to use it daily.

    Seems like the same thing happened with your Nystatin. I stopped using Ketaconozole because I didn’t want to use creams and wanted to use homeopathic / natural treatments like sea salt or apple cider vinegar that wouldn’t cause long term damage.

    My question: is Nystatin bad to use long term like hydrocortisone or Ketaconozole? Will it thin out skin like these other products?

    Reply
    • Joakim Profile Photo
      Joakim

      Hello Mr. President 🙂

      I don’t think the effect wore off in my case. I guess it was simply because I became too confident, thinking that maybe I was cured and that the SD wouldn’t come back if i stopped using nystatin. It did though 🙂 But, like I said, after a week of using it properly again the SD disappeared and I have had zero problems since then. So so far I’ve only experiences that one outbreak since December when I started using it.

      I’m still using it almost daily, so I really, really hope that it doesn’t cause long-term damage! But my dermatologist told me that I could use it daily and that I basically couldn’t use ‘too much’, so I don’t believe that the continued use is an issue. It even says so on the box from the pharmacy: “Can be used for a prolonged period of time against chronic rash in face”. Roughly translated 🙂 In the note that comes with the nystatin it says that you can apply it two to three times daily. It also says that the effect should be visible in 6 days, and that you should use it for 8-10 days afterwards to be sure to be rid of the infection. It doesn’t really say if there is a maximum of recommended use. Only that you should do, as your doctor has told you. And in my case he said ‘go ahead’.

      So I think it’s fine. In any case it is nothing like hydrocortisone. And it doesn’t feel rough on the skin like my ketoconazole-shampoo did. Like Vero said in the post above it feels non-irritating. That and the fact that my doctor and pharmacy both know that they are treating a chronic disease makes me say that you can use it long term.

      Do you know where to get it if you decide to try it?

      Reply
      • Michael A. Profile Photo
        Michael A.

        Hey Joakim,

        Thanks for checking in and keeping up to date on the comments. Glad to hear the Nystatin got things back under control so quick.

        Similar to you, I almost had a strange rebound a few weeks ago. The spots that had issues before became inflamed for a few days. Personally I got a little scared. For me, it seemed to be trigged just by being overwhelmed from school/work/life. Fortunately I was able to quickly bounce back and everything is back to normal now.

        Still working on a more integrated discussion part to the site. Haven’t had time with work, but hopefully I can add it soon. Will let you know as soon as it’s up.

        Also I’m slowly starting to write a post discussing the potential psychological part of seborrheic dermatitis. Do you think it’s possible that our strong belief in our current methods can play a role in how effective they are for us. Also on like how when things were bad, we were always second guessing ourselves, thus bringing stress and inflammation into our daily lives.

        Or do you think it’s a just a simple bacterial infection that we have managed to control?

        All the best and thanks again.

        Reply
        • Joakim Profile Photo
          Joakim

          Hi Michael,

          it’s an interesting discussion, and the easy answer is that there is probably not a simple explanation 😉

          I read a comment on one of the other discussion boards that basically said that all the stuff we try and apply to our faces doesn’t work, and that you should only worry about being happy and try new stuff. In that particular post watching good TV shows could make your seborrheic dermatitis go away. That’s not entirely untrue, but in my opinion there is so much more to it than just a state of mind.

          It is true that it helps: I experienced it in the Philippines on vacation, but aside from my mental well-being I think it was the sun and saltwater that did the trick. And I’ve also often seen a correlation between stress and aggressive flare-ups. So, it does make a difference. I think I’ve also heard stories that cancer patients who believe they will win the fight have a better chance of actually surviving cancer, rather than just giving up and giving in. This is also the reason why I looked into meditation when I was still unable to treat the seborrheic dermatitis. So I definitely think that the body and mind are connected on a level we don’t fully understand, but to say that it is the only factor is also naïve in my opinion. Modern medicine may have it’s short-comings, but to completely deny everything they have shown is a ballsy move.

          The body is a complex structure where many, many, many parts of the machine can malfunction and a lot of parts are connected in a chain, so that if one cog isn’t spinning like it’s supposed to, then it will impact something further down the line. I’m thinking genetic predisposition in one way or another to the yeast Malassezia, proper development and functioning of the immune system, healthy gut flora, proper hygiene of the skin, and probably also a calm, optimistic state of mind.

          I was very skeptical when my dermatologist handed my this ‘miracle drug’ and told me the SD would be gone in one, maybe two weeks time. I had already tried this approach and it didn’t work. So at the time I was actually looking for a cure to the root of the problem, not just treat it when it appeared. My point is, it wasn’t my optimistic, strong believe that made nystatin work in the first place. I’m a strong believer now, and the knowledge that I now have a reliable tool to treat the SD probably gives me a more relaxed mindset that, at the end of the day, is a more healthy one that will contribute to keeping the SD down.

          I’m not convinced that it’s only a matter of psychological well-being, but I guess it comes a long way. There is some microbiological stuff going on right under our noses, so to speak, and nystatin is known to bind ergosterol, which Malassezia apparently needs in its cell membrane. I believe in the scientific facts, but I am also very open-minded and fascinated by the alternative treatments, be it natural remedies or meditation and psychological well-being.

          Fun story: When I was little I hypnotized or meditated a foot wart away. I have heard that they are usually really difficult to get rid of and the treatment is quite rough (it was back then anyway), so my doctor suggested that I try to meditate and focus my mind and imagine all sorts of unpleasantries on the wart. Every night I would sit for 10-15 minutes and wish it away. Within a couple of weeks it disappeared and I haven’t had any rebounds. So I do believe in the power of the mind, but in this case with the SD I tried just about anything and nothing worked except nystatin. (except lots and lots of sun and saltwater 😉 )

          That’s my two-cents!
          Thank you for running the site, Michael. It looks like a lot of people are finding helpful information here. It’s a good community.

          Reply
  53. Vero Profile Photo
    Vero

    Hi Joakim
    Re: feedback on Nystatin. Thanks, Joakim, for the tip and for the photo of the product: Nystatin Lederle. Having ordered it (see earlier posting) I tried it for a week on the SD spots – chin, jawline, etc twice a day, morning and evening, and liked it very much.
    It did not irritate the skin and I could use other products (moisturizer, blemish treatment) over it. The SD went after about 2-3 days, I continued using the cream for a week. The last evening, I just put moisturizer on without Nystatin and the SD returned in the morning so then I went cold turkey and did not put anything on these SD spots, except for using a mild soap. No moisturizer, no blemish treatment, no Nystatin. After that the SD went away completely after 2 days so I am keeping the Nystatin in case it returns. It has been over a week now without SD so that is great.
    It worked well for me and there is a certain amount of relief that I have it on hand in case of an outbreak.
    But it was the non-irritating qualities that I liked. Anyway, that was my experience. I had ordered a 50mg tube – so that could last me even with some light re-use for over a year.
    It was a great tip so thanks very much.

    Reply
    • Joakim Profile Photo
      Joakim

      Hi Vero,
      sorry, I didn’t notice your reply until now! I am so happy to hear that it worked for you. It’s very nice to get some positive feedback, so we know it works for more people than me 😉 I’ve also been reaching out to people on Reddit, and just like you they have had positive results as well. So I’m more confident recommending it now!
      I am happy to help. Hopefully you can keep it under control. My dermatologist said that I could use it indefinitely – unlike hydrocortisone, which you should only use for 2 weeks at a time – so if you do have outbreaks then I think it would be okay to apply it daily. That’s what I do at least. But I understand if you want to keep it at a minimum 🙂
      All the best to you and your new, pretty face!

      Reply
  54. Joakim Profile Photo
    Joakim

    Hey there. I just wanted to do a little update on the nystatin. Last week I had my first flare-up since December. I think it was sparked by stress and probably also my bad habit of forgetting my daily appliance of the drug. Now, a week later, after paying more attention and never skipping a daily appliance it’s completely gone again. For a moment I was worried that the effect was wearing off, like others have experienced with other products. But I am still convinced that nystatin is very worth a shot, if you a still looking for a cure.
    I’m still looking forward to responses from those of you, who posted that you bought it. How are you doing? Are you seeing some results?
    Anyway, I wish you all the best in the search for your solution 🙂

    Reply
    • Michael A. Profile Photo
      Michael A.

      Hey Joakim,
      Thanks for the update. Hopefully some of the others manage to get good results as well. That should help in finding out if its applicable to everyone.
      All the best.

      Reply
  55. Maciej Profile Photo
    Maciej

    Unfortuntenly it doesnt work on me but I have been using suplements for 1week (biotin 10mg/ MSM 8g / capryl acid 2tabs and probiotics (acidophilus)) and my seb derm slowly disappears. If i’ll have more time I’ll write more information about this (my english is poor so I need time to write sth:P).

    Reply
    • Joakim Profile Photo
      Joakim

      Hey Maciej,
      that’s concerning news, I think. I’m sad to hear it didn’t work for you. Did you end up buying it from Germany, or did you have your friend make it? I just want to make sure that we have been using the same thing 🙂

      Reply
    • Michael A. Profile Photo
      Michael A.

      Hi Maciej,

      Sorry to hear that it didn’t work out for you. However, glad to hear the biotin combo is working.
      When I gave a similar combo a try (zinc-l-cornisone, l-glutamine, msm, biotin), I had some strange reaction to the biotin (rashes and itchy skin all over).

      Not sure if you have read over my most complete post, here.
      The methods that finally helped me (at the bottom) seem to have worked for a few others as well (check the comments).

      Thanks for taking the time to write, I understand it takes you time due to language barriers.
      Look forward to any updates and hope things work out.

      Reply
  56. Adam Profile Photo
    Adam

    Any updates with Nystatin users?

    And JOAKIM, even though you show no signs of SD, do you still apply the Nystatin cream on a daily or semi-daily basis? Im just trying to understand if you applied it initially, healed your SD, and now your not applying it at all now?

    Adam

    Reply
    • Joakim Profile Photo
      Joakim

      Hi Adam,
      yeah, I still apply it on a semi-daily basis. I don’t know that I’m cured, because I keep applying it. I will run out of my first tube soon, though, and I might just stay off and see what happens. If I relapse I guess I can always just go buy another tube and have it disappear again – unless the new, recurring SD would develop a resistance to nystatin!!! Hah, that’s my worst nightmare o.O
      So basically, I don’t know – yet – what will happen if I stop using it. I think it would come back over time. Especially since I’m not doing anything else to keep it away anymore: No saltwater cures, no strict diet, no nothing. As far as I know, it’s an ubiquitous yeast that is the cause of SD, so I don’t think there is any getting around it. At some point or another I will have it back on my nose, and my immune system wont know what to do. That’s my guess at least.

      Reply
    • Michael A. Profile Photo
      Michael A.

      Dear Vero,

      Thank you for leaving the tip. This will likely benefit any female readers stumbling through this site.
      Out of curiosity have you ever tried using the one with the sunscreen?

      Much of the information I have come across suggests the zinc oxide found in the majority of sunscreens can actually help combat it as well.

      Thanks again for the tip and best of luck.

      Reply
      • vero Profile Photo
        vero

        Thank you, Michael, for this site.
        It is really helpful to compare experiences.
        I have not tried the products or sun screens with zinc oxide but will investigate which brands might be good. Since my skin is quite oily, I was happy to discover an oil free sunscreen by Jason – which has Titanium Dioxide – but I couldn’t find zinc oxide on it – could it be the same type of ingredient? Not tested yet though.
        I have ordered Nystatin from Germany to be sent to me in the UK via http://www.parcemed.de – so will report back on how it works in the next weeks.

        In case this helps others, here is what I have tried so far. This is not very scientific – just subjective.
        1. Lamilsil – a UK brand against athlete’s foot – fungacide terbinafine hydrochloride 1 % – this worked in getting extremely inflamed skin calmed down. Used it for a week but then the effect seemed to lessen or stand still.
        2. Clarity Superdrug Skin Rescue – (UK drugstore brand) for spots -with Salicyclic Acid. This is my favorite spot fighting cream as it does not dry the skin. Helps with oiliness, does not inflame SD.
        3. Oxy on the Spot (UK brand, GlaxoKline – with Benzoyl Peroxide. A bit harsher than Clarity so I use it only on spots.
        4. 100% Tea tree oil – not bad but too harsh for longer use. Good with 100% 1:1 tea tree oil / apple cider vinegar combined on a cotton ball and brushed onto (non-inflamed) skin. But overkill for sensitive skin.
        5. For eye brows only: 1:1 apple cider vinegar on cotton balls rubbed lightly over eyebrow areas. SD completely gone after doing this twice daily for 2 days. Too harsh for rest of face. No return of SD on eyebrows 3 weeks later – only used this method for one week but the effect has lasted.
        Face washes:
        1. I used to use Clinique Facial Soap mild, – fragrance free, unisex though marketed to women. I bought some for my brother who has the same condition and he liked it. It only takes 5 splashes of water to completely wash off – used at night for many years.
        2. With the sudden SD – needed something like it but more moisturizing – so found this African Soap
        -http://www.amazon.co.uk/Genuine-African-Black-Soap-90g/dp/B00DO59YS2/ref=pd_ys_sf_s_rp_a1_2_p?ie=UTF8&refRID=1W90Y4WJRZQSH633P30G
        which moisturizes and cleans oily skin – and only 5 splashes of water needed – my best SD discovery so far.
        I do think there is a link with the gut (my SD started after food poisoning) and I do have cravings for salt (make lots of popcorn).

        I am grateful to this and other forums because for a long time I did not understand this delicate dance between oily skin and dry, flaking skin – and the product dance that goes with this. My SD is better now – much calmer – barely visible – and I look forward to testing the Nystatin. Am grateful to the contributors here.

        Reply
        • Joakim Profile Photo
          Joakim

          I am really happy about the conversation that we’re having here. For so long I was alone with my condition and I didn’t want to talk about it with friends or family. I just stayed in and hid when it got bad. I wish I had found this community sooner! It’s so nice to hear from other people fighting the fight – I think conversations like these would have kept be more hopeful when I struggled.

          Good luck with the nystatin! I hope results will be good for you too, and I’m very anxious to hear from you, when you’re a couple of weeks into the treatment.

          Reply
          • Michael A. Profile Photo
            Michael A.

            Hey Joakim,

            Hope all is well with you. Thank you for taking the time to engage on here.

            Agree with you 100% there. It was definitely hard not having anyone to really talk to about my skin.
            It felt embarrassing and I really felt doomed since the common idea is that the condition is for life.

            When things got bad, the easiest thing to do was simply hide away and keep searching the internet.

            The endless supply of poor and incomplete information on this subject was quite a hurdle to get through.
            Hopefully others can benefit from all the information that accumulates here.

            Thanks again and all the best.

        • Michael A. Profile Photo
          Michael A.

          Hi Vero,

          Thanks for the kind comments :).

          Titanium Dioxide is a bit different, but that’s actually the active ingredient in the stuff I used last summer.
          The stuff I used was Ombrelle for Kids. It was very gentle, soothed the skin, but didn’t really absorb all that well (white coating was left).
          What I felt it did though was help keep the skin from drying up from the sun while at the same time allowing me to keep my skin exposed to the sun for long periods of time (effectively killing any potential bacteria).

          However, from all the stuff I read previously, Zinc Oxide stood out as actually being able to fight the SD directly.
          This is actually one the active ingredients implemented in Sudocrem, which is commonly used for diaper rashes, eczema and other skin irritations. Here is a picture for reference.

          Additionally thank you for all the other tips.
          Look forward to any updates in terms of the Nystatin.
          Hopefully your results are similar to Joakims.

          In terms of the gut connection. Definetly something there.
          Kind of gross, but I found the my faeces used to be somewhat sticky and often left a residue on the bottom of the toilet bowl.
          Then in correlation to my L-Glutamine supplementation this went away. During the whole 8-9 past months in which my SD has been calm, I have not seen this issue.
          When researching why this could happen, everything mostly pointed to undigested fat.

          Thanks again for the all the information.
          Hope you finally find a simple approach that works for you and take care.

          Reply
        • Kepi Profile Photo
          Kepi

          Hi Vero,

          For the apple cider vinegar on brows, is it 1:1 apple cider vinegar and tea tree oil?

          Reply
          • vero Profile Photo
            vero

            Hi Kepi – and thanks, Michael for the Sudocream tip – will buy some today.
            For the eyebrows, dunk a cotton ball in any apple cider vinegar and rub over eyebrows – and slightly over and under. From my experience, this lasts a bit. Sometimes, when the eyebrows seem to tingle, I do it again. No more than once every 10 days or so. But this is too harsh on the rest of the face for me.

            I have discovered (subjectively, they seem to be good for my facial SD) 2 more products
            – for the inflamed red parts: a very cheap drugstore (Boots in the UK) branded ‘Boots Magnesium Sulphate’ Paste. It is for skin boils and infections and you just dab a very tiny bit, the size of a pin head, on the effected area overnight – stops the irritation and the flaking.

            Another hopeful discovery is plain Listerine mouthwash. I rubbed my face with it last night and it did not sting like apple cider vinegar or tea tree oil or salt solution. Then put a mild oil-free moisturizer on (still not happy on the moisturizer front – any suggestions?) and the effect was very very good. Listerine contains not just anti-bacterial properties but also anti-fungal ones – so works on the oiliness of the skin as well. Will wait for the Nystatin and report back.

          • Michael A. Profile Photo
            Michael A.

            Hi Vero,

            The Sudocream was best of the corners of the mouth when I had issues there. For larger areas it was quite difficult to wipe/clean off.
            It would typically leave white residue on my face. Unless I washed it off with soap, but this would then bring back the SD quicker.

            Haven’t heard of the Magnesium Sulphate paste stuff before. Might be interesting though.
            The anti-fungal aspect of that is likely why it works well for the seborrheic dermatitis.

            In terms of the Listerine, I’ve actually come across that approach as well.
            However, I never attempted using it though. It seems like it’s the anti-fungal aspect at work here as well.

            Look forward to hearing your update with the Nystatin.
            Thanks again for updating and best of luck.

  57. Ron Profile Photo
    Ron

    Hi Joakim, thanks for sharing this. I also have SD and planning to buy Nystatin Lederle creme soon!

    Reply
    • Joakim Profile Photo
      Joakim

      No problem, Ron! I am happy to hear that. Hopefully, you will see the same incredible recovery that I experienced. So far, actually, no one has reported back to me after I recommended them Nystatin, so I am still very anxious to hear if other people will have the same experience!
      Where are you from? Have you figured out a way to purchase it? It could be helpful to other people if they are from the same country but are having problems locating a seller 🙂

      Reply
  58. Vincent Profile Photo
    Vincent

    I have tried many natural remedies and prescription drugs. Currently, I’m on 1% ciclopirox. I don’t have flaking, just red inflamed skin on my chin and nasal folds. 2 dermatologists have said it is seb derm. However, nothing has healed the face redness as of yet.

    Joakim – How long did you use the Nystatin before you saw improvement with the redness? And how long until you experienced complete remission of the skin redness?

    I really appreciate your help!

    Reply
    • Joakim Profile Photo
      Joakim

      If I recall correctly I started using nystatin around December 8th and by Christmas Eve it was gone. I think I started seeing improvements after the first week or so. It was a pretty fast process of recovery, actually. I used it daily at the time. Now, I tend to forget 2 days a week or so, but in the beginning I was on point!
      My dermatologist sounded very confident when he prescribed me the stuff. He was like “Try this and I bet you’ll see improvements by the end of week the. Otherwise come see me again.” Now I wonder what he would have done, had I come back. Maybe he was just reassuring me, and he knew I wouldn’t come back.
      I’d recommend you trying it if you have the possibility. I also tried other anti-fungals that didn’t do it for me. I think ciclopirox and nystatin work differently, so there’s hope! 🙂

      Reply
      • HopeDiesLast Profile Photo
        HopeDiesLast

        Hi, Joakim, MICHAEL , all

        Thanks for sharing your story with us, i have SD(seborrheic dermatitis ) 10 years now and i have tried almost everything to control it. What i found to be effective was keep washing my face once daily(at night usually) with a no-soap cleanser which doesn’t dry my skin applying aloe vera moisturizer when my skin looks dry and when a rush appears using once daily ketoconazole cream(fungoral is the brand’s name) for 7 days. The first 1-2 days my skin reacts and doesn’t like it but then at day 2 or 3 it calms down and you couldnt tell i had a rush there.I also save every second day because if i dont my skin becomes flaky , and i apply fresh aloe vera from the plant to me face whenever i can.For my scalp i am using a shampoo that doesnt dry my skin out and ACV remedy some days per week.

        I am interested on what you suggested (Nystatin cream) because i believe we should check all of our options and i am currently trying to find alternatives that work better than the solutions i’ve already found.

        My questions are :
        1) how many times per day and how many days in a row did you apply the Nystatin cream)?
        2) what is your maintenance routine after you controlled SD?
        3) what other things are you doing in order to help your SD not coming back?

        Thank you MICHAEL for this beautiful site and i am looking forward to your answear joakim
        HopeDiesLast

        Reply
        • Michael A. Profile Photo
          Michael A.

          Dear Friend,

          Thank you for the positive comment. Glad to hear you found a way to partially control it.
          Hopefully Joakim can provide you will some more details.

          Similar to you I only wash my face once a day in the evening and always with cold water.
          What cleanser are you currently using as a daily wash? (question was answered in another comment, HopeDiestLast uses La Roche Posay Toleriane).

          All the best.

          Reply
        • Joakim Profile Photo
          Joakim

          Hi HopeDiesLast,
          I’m happy to hear that you have control over your SD. However, my experience with Nystatin has cured me to a degree where I don’t have any maintenance routines anymore – well, except that I still use Nystatin and a dandruff shampoo (containing zinc pyrithione and climbazole as described above) from time to time. So I recommend that you try it if you have the possibility.
          1) I apply Nystatin once every day after I shower – doesn’t really matter if it’s morning/evening/after workout. I’ve been using it since December (it took about two weeks for it to clear up my face) and I still use it on a semi-daily basis. I’ve gotten very forgetful for the past few weeks and that doesn’t seem to cause any trouble. The SD is under pretty good control in my opinion! And I wash my hair with shampoo maybe 2-3 times a week. Again, it’s not really critical to be super strict!
          2) Since I’ve gotten it under control I don’t follow any special routines. I still take the remaining supplements I have, but I don’t think I will restock once I eat all of them and I don’t think that will cause any problems. We’ll see. I’ll report back if I get horrible flare-ups once I stop with my vitamin-D! 🙂
          3) Nothing really. I mean, I try to exercise and eat healthy, but sometimes I binge. And even before exercise would also be a bad thing! So all the previous no-go’s like coffee, alcohol, hot showers and poor sleep doesn’t do anything. I can go to work on a Friday, have several cups of coffee, meet up with friends afterwards and have several beers and party all night and have a nice hot shower in the morning without issues. My skin might feel a little tight after a night like that, but I just rehydrate and everything is alright.
          Oh wait, I guess I make sure I drink plenty of water every day, and I severely cut back on my milk consumption, but I don’t really think it would make a difference if I started drinking milk again. I still eat cheese, so I don’t see why milk would be a problem. I think that are the only real changes I have made.
          So even though you seem to have your SD under control I recommend that you try Nystatin, since I think it could give you a more care-free life without maintenance routines and occasional flare-ups!
          All the best,
          Joakim

          Reply
  59. Vincent Profile Photo
    Vincent

    Hi Joakim.

    Thanks for sharing your battle with SD. What symptoms did you have on your face? Was it red inflamed skin or more mild flaking only? What areas were affected?

    Reply
    • Joakim Profile Photo
      Joakim

      Hi Vincent,
      it was the double-trouble of both flaking and red, inflamed skin. During flareups it would also itch to some extent. I had spots of it on my scalp, my forehead, the skin under and close to my eyebrows, the sides of my nose and parts of my cheeks and throat when it got really bad. I also had a small area of it on my chest, similar to where Superman would have his logo or where Ironman has his power-core thingy, although I didn’t feel very super at the time 🙂
      As I recall the shampoo alone got the inflammation on my scalp down. It would still flake, but the skin didn’t look red at least. But by just using the nystatin creme on my face it cleared up the rest of the flaking from my scalp (while still using the shampoo) and the area on my chest as well. To me that’s almost the most impressive thing.
      What have you tried so far?

      Reply
  60. Maciej Profile Photo
    Maciej

    Hi, Could you upload photo of your cream facts? In my country this is of course prescription drug but there are many nystatin creams with different bases. As you wrote in another post seb derm like oils so what should be the base of cream to do not feed seb derm?

    Sometimes I read in Internet about cream with Sulfacetamide 10% and sulfur 5% whitch helps a lot in seb derm and rosacea, Did you heard about it?

    Thanks a lot for help, and sorry for my english.

    Regards

    Reply
    • Joakim Profile Photo
      Joakim

      Hi Maciej,
      I can’t find a photo that shows the facts, and the only websites I can find are in German, but I’ll translate:

      “1 g creme contains as the active ingredient: 100.000 IE Nystatin corresponding to 22,73 mg dry-matter.
      Other Ingredients: Macrogol stearat 1000 [a different name for polyethylene glycol], cetostearyl alcohol, isopropyl myristate, glycerol 85%, sorbic acid (E200), lactic acid (E270), sodium hydroxide, purified water.”

      But this is not meant as a moisturizer. The point of nystatin is not to avoid feeding the malassezia yeast, it is to use an anti-fungal to kill the yeast, so you don’t have to worry about moisturizing. I don’t know why the first anti-fungal I tried didn’t work (specifically miconazole combined with hydrocortisone in a creme). I read somewhere on wikipedia that their ways of killing the yeast are different. The azoles are lanosterol 14
      alpha-demethylase inhibitors, while nystatin works by ergosterol binding – it has to do with their cell membranes. Anyhow, the details are not important to us, the important thing to learn from this is that “anti-fungal” is a broad term and it would be a mistake to think no anti-fungal will work simply because one didn’t. So try another angle of attack 🙂

      Personally I haven’t heard of sulfacetamide 10% and sulfur 5% or tried it on myself, but wikipedia says it is a suggested treatment. Maybe Michael has some experience with it?

      Reply
      • Michael A. Profile Photo
        Michael A.

        Hi Maciej,

        Not sure, but I believe I remembers stumbling upon the sulfacetmatide and sulfur products. Think I found them when I was looking for a Lotramin Ultra alternative for the face.

        Personally I never ended up ordering any of the sulfacetmatide and sulfur products because I couldn’t find enough safety information. Also the main place to buy it was eBay (no listings on Amazon), so I wasn’t sure how the product was regulated/produced.

        Reply
      • Maciej Profile Photo
        Maciej

        Thanks a lot for answer. I have friend whos working in pharmacy and he could make me cream because in PL we dont have nystatin cream – nystatin is only in form granules and infusion. Unfortunately components from your cream arent avalible in pharmacys (only in larger production) but I hope that friend use good components – I told him to avoid from using oils.

        I don’t understand second part of your post: “But this is not meant as a moisturizer. The point of nystatin is not to avoid feeding the malassezia yeast, it is to use an anti-fungal to kill the yeast, so you don’t have to worry about moisturizing.” Cound you write more clearly? My english is quite bad sorry.

        Reply
        • Joakim Profile Photo
          Joakim

          Hi Maciej,
          I found a website that looks like it sends nystatin to most European countries – including Poland. Otherwise, it’s an over-the-counter drug in Germany, so if you go to Germany you can buy it without a prescription from your doctor. Anyway, here is the website if your friend cannot help you make it: http://www.apons.eu/nystatin-lederle-creme

          The point I was trying to make is this: With nystatin you are killing the SD. The reason we should avoid oils is that we don’t want to feed the SD, but when we have already killed it then it doesn’t matter with the oils.
          I have completely stopped using moisturizers since I got nystatin. I don’t get dry, red skin anymore so there is no need to moisturize (with or without the oils). I hope that makes more sense – otherwise just ask again if there is something you want me to explain better 🙂

          Best of luck!

          Reply
          • Maciej Profile Photo
            Maciej

            Hi Joakim,
            Thank you very much:) I wrote to few eshops from Germany about ordering nystatin cream – we will see what they answer about buying from Polnad. Anyway thanks again for help.

            Now I understand you 🙂 You give me a hope to cure for this terrible disease!

            🙂

        • Joakim Profile Photo
          Joakim

          I am happy to help! But before I get your hopes up, I’d just like to clarify something: If this works for you it probably doesn’t mean that you will be cured. I don’t consider myself cured – not totally. I think SD comes from a problem in our immune systems; Everybody has the SD yeast on their skin, but most people can fight it naturally through their immune system. But we have some defect that can’t handle the SD yeast. So we need some help, and that help can be nystatin or ketoconazole or green tea or whatever works for people. But I think we will always have that defect, so we have to keep treating it – unfortunately.
          So maybe we will never really be *cured*, but so far – after I started using nystatin – I *look cured*, and I guess that’s the most important thing 🙂

          Reply
        • Mathieu Profile Photo
          Mathieu

          Możesz mi powiedzieć czy dostałeś ten krem? Podlinkuj proszę, tak się składa, że też jestem Maciej z SD. Czekam z niecierpliwością, w ostateczności będę musiał wyskoczyć do Berlina.

          Reply
          • Maciej Profile Photo
            Maciej

            Sorry for no reply. Nystatin cream didnt help me. Now I am on diet – no sugar, no milk, no gluten, a lot of meet and vegetables – i want to rebuild my flora and It probably helps. After 5weeks of this diet my seb derm slowly dissapearing.
            I will write more after 2-3month when I will be sure that it helps me.

            To mathieu – kupiłem w http://www.apons.eu/, ale jeśli chcesz mogę Ci sprzedać mój kream bo mi nie pomógł. Ja mam ŁZS już od 8-9lat i mam zaawansowane stadium i tak jak pisze wyżej musze leczyć się od środka – odbudować florę bakteryjną, zmniejszyć porowatość jelit, wyleczyć zagrzybienie układu pokarmowego. Póki co widzę rezultaty po 5tygodniach.
            Stosuję Dietę Prozdrowotną i Miksturę Oczyszczającą z bioslone.pl

            Pozdro

          • Michael A. Profile Photo
            Michael A.

            Hi Maciej,
            Sorry to hear the Nystatin didn’t work for you. However, glad to hear the diet approach is working. 🙂
            Since your Polish (of of similar descent as me) and the diet approach is working, I think I have further information that might benefit. I’ve sent you an a direct email with details.

            Best of luck.

  61. Anna Profile Photo
    Anna

    Thanks guys!

    Just so you know. I’ve been religiously washing the affected areas (jaw area) with sea salt and have been applying KETOCONAZOLE which my doctor says is the generic name for NYSTATIN. I don’t know if this is true though.

    So far, the salt wash has helped tremendously in reducing the swelling / flare up. I just started Ketaconozole yesterday so let’s see what happens.

    Grateful for your time.

    Reply
    • Michael A. Profile Photo
      Michael A.

      Hi Anna,

      Glad to hear your seeing some improvements.
      Hopefully the Ketoconozole will help as well.

      Strange that the doc said that they are the same as they are actually different.
      For example here is a study that compares the two: http://www.ncbi.nlm.nih.gov/pubmed/3905986

      They are both anti-fungals and serve a similar purpose. Ketoconozole is actually the active ingredient in Nizoral dandruff shampoo. Here in Canada it is sold over the counter without any prescription. The shampoo didn’t work out for me as it was really harsh on the skin. However, I’ve read some people have great success with it.

      Would be interesting to hear about your experience with it.

      Reply
  62. Anna Profile Photo
    Anna

    Thanks for sharing.

    I live in Manila and am wondering if i could get Nystatin here. Is that the brand name? The ones i seen online are for vaginal infections. May i ask which one you used?

    Reply
    • Michael A. Profile Photo
      Michael A.

      Hi Anna,

      Nystatin is the name of the actual anti-fungal agent. There are many brand names for it.
      Wikipedia has some details on it.

      I have also sent Joakim an email with your question.
      Hopefully he can help clarify which specific one he’s using.

      Reply
      • Anna Profile Photo
        Anna

        Thanks Michael,

        My SD is not that bad but it is all over the lower half of my face. It’s quite debilitating as my profession needs me to meet with many people.

        I guess I might as well bring it up here just in case you have any leads…. any clues about the best make-up for people with SD?

        Thanks for forwarding my message to Joakim.

        Reply
    • Joakim Profile Photo
      Joakim

      Hi Anna,
      sorry about the mix-up! I guess that goes to show that it’s always a good idea to double-check the helpful advice you find online, or to talk about it with a professional.
      Anyhow, the one I use is called Nystatin Lederle Creme and contains 25 g per tube. Actually, it doesn’t say anywhere on the packaging that it’s for SD, it just says it for fungal-infections so there might not be a distinction between creme from oral-, topical- or vaginal application. My guess is that any creme with nystatin as the active drug will do the trick, but I’m not a doctor, so you’d better consult one anyway 🙂
      I found an image of the one I have at home: http://tinyurl.com/k8xg7q9. Maybe that will make it easier for you to compare. They might not have exactly the same one in the Philippines or even the US. It might be possible to buy it online from Germany since it’s an over-the-counter drug, but I haven’t looked into that yet. Let me know if you can’t find anything locally, then I will look into the possibility of buying it online and having it delivered. It doesn’t make any sense for me to spread the word about this if no one can get a hold of the drug unless they are in Denmark or Germany 🙂
      I hope you can find a similar one, though! I really think it will do the trick.
      Best of luck,
      Joakim

      Reply
      • Anna Profile Photo
        Anna

        Thanks for your reply Joakim.

        I’ll definitely call my dermatologist, who by the way keeps on insisting on a cotrisol cream. I’ve given up on that since it doesn’t really make it go away completely plus it a few days later it get really bad after using it.

        Wanted to share with you as well that at the moment, what I’m doing is the salt water treatment that I’ve been reading about online. It’s my 2nd day and it seems that the flaring has improved. It’s still visible and still inflamed but I think there is some improvement.

        Also, would you know anything about DermaZinc? BHA Exfoliants?

        Will let you know if I’m able to find Nystatin here.

        Grateful for your help,

        Anna

        Reply
        • Joakim Profile Photo
          Joakim

          I guess *that* goes to show that sometimes you have to start digging around the internet for solutions when your own dermatologist can’t do his job! I’ve read countless times that the prolonged application of hydrocortisone is a bad idea, so that doesn’t give me a whole lot of faith in your dermatologist, I’m afraid. Tell him that it doesn’t work and that you want an alternative.
          I’m happy to hear that the sea water treatment is working out for you. It’s such a relief to make some progress. I also recommend going to Palawan to get the full-on sun & saltwater treatment! That cured me while I was there 😉

          I haven’t hear about DermaZinc but it sounds like something that might work. I guess it has zinc pyrithione like my shampoo and head&shoulders. Generally, I’ve heard good things about that, but for me it didn’t change my face, and my scalp wasn’t really cured until I started using nystatin on my face: Only then did I get rid of the whole thing – it’s sort of weird actually.
          I never tried exfoliants, so I’m not sure about it, but I had bad experiences trying to cleanse my way out of the flare-ups. It might just give the Malassezia yeast more room or better conditions, I’m not sure – but it probably wont kill it like your aiming for. Unfortunately.

          But if both things are over the counter you might as well try them out. I had to go through a lot of trial and error, but it seems that a lot of people find different solutions, so DermaZinc or BHA might be it for you. I just recommend nystatin, since that worked for me. Other anti-fungals might work to the same extent, so if you cant find nystatin specifically, it might be worth giving something like sertaconazole or miconazole a shot. But now we’re getting to that part again, where I’m passing medical advice like I’m a doctor – which I’m not. I haven’t had experience with sertaconazole or miconazole, but desperate times calls for desperate measures. At least they’re some alternatives that you can discuss with your dermatologist.

          Fingers crossed!

          Joakim

          Reply
        • Michael A. Profile Photo
          Michael A.

          Hi Anna,
          The DermaZinc is essentially the same as Head and Shoulders. Previously I have tried similar products from Noble Formula (tried the bar soap and the cream), it’s basically identical to the DermaZinc and sold on Amazon as well. My results were mixed. It worked really well at first. For 3-4 weeks my face was totally clear. Then it just seemed to stop doing it’s job. Also it made the skin quite a bit less healthy looking in general and quite sensitive to the sun. The reviews on Amazon for this stuff are fantastic though and based on those lot’s of people find success with it (there are also some who describe same experience as me).

          As for make up I have no idea since I’m a male. What I remember reading though, was that some women had great results with make up that contained UV protection. It is common to use zinc oxide as a UV protecting agent in skincare products. And zinc seems to actually benefit in reducing the SD.

          Good luck and hope your progress continues.

          Reply
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